ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2021
Excess Risk of Tuberculosis Infection Among Extra-household Contacts of Tuberculosis Cases in an African City.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Article
- Rural Residence and One-Person Households Are Associated with Diagnostic Delay in Pulmonary Tuberculosis in a Low-Incidence European Setting.Tropical medicine and infectious disease · 2026Article
- A Bayesian Framework for the Network Analysis of Transmission Dynamics in Infectious Disease.Journal of molecular evolution · 2026Article
- Machine Learning Models for Predicting Latent Tuberculosis Infection Risk in Close Contacts of Patients with Pulmonary Tuberculosis - Henan Province, China, 2024.China CDC weekly · 2026Article
- Culturally relevant settings for TB transmission in an African city with endemic TB.IJTLD open · 2025Article
- The Role of Community Networks in the Transmission and Persistence ofOpen forum infectious diseases · 2025Article
- Burden of pulmonary tuberculosis among Ethiopians seeking jobs in the Middle East: a retrospective study.BMC public health · 2025Article
- Alcohol Consumption of Male Tuberculosis Index Cases and Tuberculosis Transmission Among Social Contacts in Puducherry, India: A Cross-Sectional Analytical Study.Tropical medicine and infectious disease · 2025Article
- Bayesian estimation of transmission networks for infectious diseases.Journal of mathematical biology · 2025Article
- Performance of a score to characterise adequate contact among the social network of persons with TB.IJTLD open · 2024Article
- Article
- Accuracy of Inferences About the Reproductive Number and Superspreading Potential of SARS-CoV-2 with Incomplete Contact Tracing Data.Research square · 2023Article
- The Association Between Social Network Characteristics and Tuberculosis Infection Among Adults in 9 Rural Ugandan Communities.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Article
- Pulmonary tuberculosis vs. Tindzhaka and Mafularha: A mixed methods inquiry of traditional healers' perceptions of tuberculosis in rural South Africa.PLOS global public health · 2023Article
- Prevalence of latent tuberculosis infection among participants of the national LTBI screening program in South Korea - A problem of low coverage rate with current LTBI strategy.Frontiers in public health · 2022Article
- Association between tuberculosis in men and social network structure in Kampala, Uganda.BMC infectious diseases · 2021Article
- Assessing a transmission network of Mycobacterium tuberculosis in an African city using single nucleotide polymorphism threshold analysis.MicrobiologyOpen · 2021Article
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8 authors.
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Abstract
backgroundAlthough households of tuberculosis (TB) cases represent a setting for intense transmission of Mycobacterium tuberculosis, household exposure accounts for <20% of transmission within a community. The aim of this study was to estimate excess risk of M. tuberculosis infection among household and extra-household contacts of index cases.
methodsWe performed a cross-sectional study in Kampala, Uganda, to delineate social networks of TB cases and matched controls without TB. We estimated the age-stratified prevalence difference of TB infection between case and control networks, partitioned as household and extra-household contacts.
resultsWe enrolled 123 index cases, 124 index controls, and 2415 first-degree network contacts. The prevalence of infection was highest among household contacts of cases (61.5%), lowest among household contacts of controls (25.2%), and intermediary among extra-household TB contacts (44.9%) and extra-household control contacts (41.2%). The age-adjusted prevalence difference between extra-household contacts of cases and their controls was 5.4%. The prevalence of infection was similar among the majority of extra-household case contacts and corresponding controls (47%).
conclusionsMost first-degree social network members of TB cases do not have adequate contact with the index case to experience additional risk for infection, but appear instead to acquire infection through unrecognized exposures with infectious cases in the community.
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