ArticleJournal of vision2020
Combining fixation and lateral masking training enhances perceptual learning effects in patients with macular degeneration.
Article in Journal of vision, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 18 citations in OpenAlex.
- Efficacy of binocular vision training and Fresnel press-on prism on children with esotropia and amblyopia.International ophthalmology · 2023Trial
- Distinct roles of central and peripheral vision in rapid scene understanding.Journal of vision · 2026Article
- Spatial remapping improves reading with simulated central field loss.Journal of vision · 2026Article
- Video-evoked neuromarkers of visual function in age-related macular degeneration.Frontiers in human neuroscience · 2025Article
- PLFest: A New Platform for Accessible, Reproducible, and Open Perceptual Learning Research.Journal of cognitive enhancement : towards the integration of theory and practice · 2024Article
- tRNS boosts visual perceptual learning in participants with bilateral macular degeneration.Frontiers in aging neuroscience · 2024Article
- Empowerment-Based Physical Activity Intervention for People with Advanced Dry Age-Related Macular Degeneration: Mixed-Methods Protocol.International journal of environmental research and public health · 2022Article
- Oculomotor changes following learned use of an eccentric retinal locus.Vision research · 2022Article
- Optic Flow Processing in Patients With Macular Degeneration.Investigative ophthalmology & visual science · 2022Article
- Current directions in visual perceptual learning.Nature reviews psychology · 2022Article
- Perspectives on the Combined Use of Electric Brain Stimulation and Perceptual Learning in Vision.Vision (Basel, Switzerland) · 2022Article
- Training peripheral vision to read: Using stimulus exposure and identity priming.Frontiers in neuroscience · 2022Article
- A randomized study of network-based perception learning in the treatment of amblyopia children.International journal of ophthalmology · 2022Article
- Perspective on Vision Science-Informed Interventions for Central Vision Loss.Frontiers in neuroscience · 2021Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Macular degeneration (MD), a retinal disease affecting central vision, represents the leading cause of visual impairment in the Western world, and MD patients face severe limitations in daily activities like reading and face recognition. A common compensation strategy adopted by these patients involves the use of a region in the spared peripheral retina as a new fixation spot and oculomotor reference (preferred retinal locus, or PRL). Still, peripheral vision is characterized by poorer visual acuity, fixation stability, and larger crowding zones that further hinder processes like object recognition, visual search, and reading. Perceptual learning (PL) has been successfully used to improve visual acuity in mild visual conditions (e.g., presbyopia, amblyopia and myopia), but results in MD are less clear, often showing limited generalization of learning, unlike what is observed in a healthy population. A possible reason is the suboptimal fixation in the PRL that might prevent patients from processing the briefly presented training stimuli. Following this hypothesis, we trained five MD patients and four age- and eccentricity-matched controls with a protocol that combined contrast detection and a task previously used to train fixation stability. Results showed transfer of learning to crowding reduction, reading speed, and visual acuity in both MD patients and controls. These results suggest that in the case of central vision loss, PL training might benefit from the integration of oculomotor components to optimize the effect of training and promote transfer of learning to other visual functions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.