Evidence map›Paper›PMID 33063899›Full record

ArticleInternational journal of clinical practice2021

Is there any association of COVID-19 with testicular pain and epididymo-orchitis?

Caner Ediz, Hasan Huseyin Tavukcu, Serkan Akan, Yunus Emre Kizilkan, Adem Alcin, Kerem Oz, Omer Yilmaz

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 3 pooled it
10.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 61 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Urological complications of COVID-19: a systematic review.International braz j urol : official journal of the Brazilian Society of Urology
    Pooled it
  4. COVID-19 Infection, Drugs, and Liver Injury.Journal of clinical medicine · 2025
    Review
  5. Article
  6. Article
  7. SARS-CoV-2 and male infertility: from short- to long-term impacts.Journal of endocrinological investigation · 2023
    Review
  8. Review
  9. Article
  10. Long COVID and hypertension-related disorders: a report from the Japanese Society of Hypertension Project Team on COVID-19.Hypertension research : official journal of the Japanese Society of Hypertension · 2023
    Review
  11. Article
  12. Review
  13. Review
  14. Investigating Impacts of CoronaVac Vaccination in Males onThe world journal of men's health · 2022
    Article
  15. Observational
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Caner EdizDepartment of Urology, Sultan Abdulhamid Han Education and Research Hospital, Istanbul, Turkey.ORCID https://orcid.org/0000-0001-9717-1209
Hasan Huseyin TavukcuDepartment of Urology, Sultan Abdulhamid Han Education and Research Hospital, Istanbul, Turkey.
Serkan AkanDepartment of Urology, Sultan Abdulhamid Han Education and Research Hospital, Istanbul, Turkey.ORCID https://orcid.org/0000-0002-6066-0401
Yunus Emre KizilkanDepartment of Urology, Sultan Abdulhamid Han Education and Research Hospital, Istanbul, Turkey.
Adem AlcinDepartment of Urology, Sultan Abdulhamid Han Education and Research Hospital, Istanbul, Turkey.
Kerem OzDepartment of Urology, Sultan Abdulhamid Han Education and Research Hospital, Istanbul, Turkey.
Omer YilmazDepartment of Urology, Sultan Abdulhamid Han Education and Research Hospital, Istanbul, Turkey.
Suleyman Demirel University Research and Education Hospital · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThis study aims to analyse the novel Coronavirus disease- (COVID-19) related testicular pain in hospitalised patients because of COVID-19 and to review as an aetiological factor for epididymitis, orchitis or both.

methodsA total of 91 patients were included in the study. A questionnaire was formed for the questioning of testicular pain or epididymo-orchitis in patients with COVID-19. Demographics and past medical history was also recorded. Patients' neutrophil and lymphocyte counts, neutrophil-lymphocyte ratios (NLR), C-reactive protein (CRP) levels and D-dimer values were recorded. Patients with COVID-19 were divided into two groups according to absence or presence of testicular pain or epididymo-orchitis as group 1 and group 2. All results were compared for both groups.

resultsThe median age of patients was similar in both groups. Testicular pain was occurred in 10.98% of the patients. Clinical presentation of epididymo-orchitis was diagnosed in only one patient. No statistically significant difference was reported in terms of patients' age, levels of CRP and D-Dimer or NLR and results of questionnaire form queries between the two groups (P > .05).

conclusionTesticular pain was observed more frequently in hospitalised COVID-19 cases. While no inflammation marker which is related to predict of testicular pain or epididymo-orchitis was found in patients with COVID-19.

Indexed as

COVID-19EpididymitisOrchitisHumansMalePainSARS-CoV-2

Identifiers

PMID33063899
PMCPMC7646040
OpenAlexW3093411245

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.