ArticleSports medicine (Auckland, N.Z.)2021
Associations of Objectively Measured Physical Activity and Sedentary Time with the Risk of Stroke, Myocardial Infarction or All-Cause Mortality in 70-Year-Old Men and Women: A Prospective Cohort Study.
Article in Sports medicine (Auckland, N.Z.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
37 citing papers in PubMed, 3 syntheses or guidelines pooled it, 80 citations in OpenAlex.
- Pooled it
- Combined exercise training to improve gait in older stroke patients: a systematic review and network meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Pooled it
- Objectively determined physical activity and adiposity measures in adult women: A systematic review and meta-analysis.Frontiers in physiology · 2022Pooled it
- Associations between 24-hour movement behavior and non-suicidal self-injury in adolescents: based on compositional data and isotemporal substitution analysis.BMC psychology · 2026Article
- Effects of reducing sedentary behaviour on cardiovascular health, skeletal muscle oxidative capacity and functional exercise capacity in sedentary adults: a randomised controlled trial.BMJ open sport & exercise medicine · 2026Article
- The relationship of physical activity and sedentary behavior patterns with osteoporosis in older women: a dose-response analysis.Frontiers in public health · 2026Article
- The Association Between Sedentary Behavior and Cardiovascular Disease Risk: An Analysis Based on NHANES Data.Cardiovascular therapeutics · 2026Article
- Physical activity, muscle strength, sedentary behavior, sleep, and genetic risk of stroke and dementia: findings from a large cohort study.BMC public health · 2025Article
- Association of Life's Crucial 9 with the risk of all-cause and cardiovascular mortality among US patients with stroke.Medicine · 2025Article
- The influence of cardiovascular fitness and ventilatory efficiency on fMRI assessed cerebrovascular reactivity in older adults.Frontiers in physiology · 2025Article
- Objectively Measured Physical Activity and Sedentary Behaviour on Cardiovascular Risk and Health-Related Quality of Life in Adults: A Systematic Review.Healthcare (Basel, Switzerland) · 2024Review
- The association between objectively-measured sedentary behavior patterns and predicted 10-year ASCVD risk.Scientific reports · 2024Article
- Associations between accelerometer-measured physical activity and sedentary behaviour with physical function among older women: a cross-sectional study.BMC public health · 2024Article
- Association of Life's essential 8 score with the risk of all-cause mortality and cardio-cerebrovascular mortality in patients with stroke.BMC cardiovascular disorders · 2024Article
- Association between physical activity changes and incident myocardial infarction after ischemic stroke: a nationwide population-based study.BMC public health · 2024Article
- The global burden of ischemic heart disease attributed to high fasting plasma glucose: Data from 1990 to 2019.Heliyon · 2024Article
- 2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association.Circulation · 2024Review
- Effects of physical activity and sedentary behaviors on cardiovascular disease and the risk of all-cause mortality in overweight or obese middle-aged and older adults.Frontiers in public health · 2024Article
- Replacing device-measured sedentary time with physical activity is associated with lower risk of coronary heart disease regardless of genetic risk.Journal of internal medicine · 2024Article
- Test-Retest Reliability, Agreement and Criterion Validity of Three Questionnaires for the Assessment of Physical Activity and Sedentary Time in Patients with Myocardial Infarction.International journal of environmental research and public health · 2023Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
objectiveTo study the associations of objectively measured physical activity (PA) and sedentary time (ST) with the combined outcome of incident stroke, myocardial infarction (MI) or all-cause mortality in older adults.
methodsN = 3343 men and women aged 70 who participated in a health survey between 2012 and 2017 were included. Actigraph GT3X+ accelerometers were used to measure light-intensity PA (LPA), moderate-intensity PA (MPA) and ST for 1 week. Incident cases of cardiovascular disease (CVD) in terms of stroke or MI, and all-cause mortality were identified using national registers. Hazard ratios (HR) and 95% confidence intervals (CI) were estimated using multivariable-adjusted Cox regressions.
resultsDuring a mean follow-up of 2.7 years (0.1-5.6), there were 124 events of CVD or all-cause mortality. After adjusting for potential confounders and mediators, every 30-min/day increment in LPA was associated with 11% lower risk of CVD or all-cause mortality (HR 0.89, 95% CI 0.82-0.97), and every 30-min/day increment in MPA was associated with 36% lower risk (HR 0.64, 95% CI 0.48-0.84). Every 1-h/day increment in ST increased the risk of the outcomes by 33% (HR 1.33, 95% CI 1.14-1.56), although there was no significant association among participants who performed ≥ 30 min/day MPA (HR 1.11, 95% CI 0.82-1.50, P = 0.034 for interaction). None of the associations were modified by sex (P > 0.4 for all).
conclusionObjectively measured LPA and MPA are each associated with lower risk of stroke, MI or all-cause mortality in 70-year-old individuals, while ST is associated with increased risk. The greatest risk reduction is observed for MPA, which also appears to attenuate some of the increased risks associated with ST.
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Registered trials
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