Evidence map›Paper›PMID 33063240›Full record

ReviewCurrent atherosclerosis reports2020

The Role of the Gut Microbiota in Coronary Heart Disease.

Huagang Liu, Junli Zhuang, Peng Tang, Jie Li, Xiaoxing Xiong, Hongping Deng

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current atherosclerosis reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  9. Multi-omics analysis identifiesFrontiers in microbiology · 2025
    Article
  10. Review
  11. The gut microbiome, chronic kidney disease, and sarcopenia.Cell communication and signaling : CCS · 2024
    Review
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  13. Article
  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Huagang LiuDepartment of Vascular Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, Hubei Province, China.
Junli ZhuangDepartment of Vascular Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, Hubei Province, China.
Peng TangDepartment of Vascular Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, Hubei Province, China.
Jie LiDepartment of Vascular Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, Hubei Province, China.
Xiaoxing XiongDepartment of Neurosurgery, Renmin Hospital of Wuhan University, 99 Zhang Zhidong Rd, Wuhan, 430060, Hubei Province, China. xiaoxingxiong@whu.edu.cn.
Hongping DengDepartment of Vascular Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, Hubei Province, China. hpdeng@whu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThis review focuses on recent evidence examining the role gut microbiota play in coronary heart disease. It also provides a succinct overview of current and future therapies targeting the gut microbiota for coronary heart disease risk reduction. RECENT

findingsA consensus has been reached that differences exist in the gut microbiotas of patients with coronary heart disease. Studies have shown that the gut microbiota is associated with obesity, diabetes, dyslipidemia, and hypertension, which are risk factors for coronary heart disease. The gut microbiota is involved in mediating basic metabolic processes, such as cholesterol metabolism, uric acid metabolism, oxidative stress, and inflammatory reactions, through its metabolites, which can induce the development of atherosclerosis and coronary heart disease. Interfering with the composition of gut microbiota, supplementing probiotics, and fecal donation are active areas of research to potentially prevent and treat coronary heart disease. Gut microbiota are causally associated with coronary heart disease. We analyzed the gut microbiota's effects on risk factors for coronary heart disease and studied the effects of gut microbiota metabolites on coronary heart disease. Gut microbiota is a potential target for preventing and treating coronary heart disease.

Indexed as

Gastrointestinal MicrobiomeAnimalsCholesterolCoronary DiseaseDiabetes ComplicationsDyslipidemiasHumansHypertensionInflammationMiceObesityOxidative StressProbioticsRisk FactorsUric AcidCholesterolUric AcidCoronary heart diseaseGut microbiotaInflammatoryIntestinalObesity

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.