Evidence map›Paper›PMID 33063191›Full record

ArticleDigestive diseases and sciences2021

Impaired Quality of Working Life in Inflammatory Bowel Disease Patients.

Sara van Gennep, Nanne K H de Boer, Marieke E Gielen, Svend T Rietdijk, Krisztina B Gecse, Cyriel Y Ponsioen, Marjolijn Duijvestein, Geert R D'Haens, Mark Löwenberg, Angela G E M de Boer

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Digestive diseases and sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05906043 (A Multidisciplinary Approach to Assessing and Treating Fatigue in Inflammatory Bowel Disease), which is not on this map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05906043 naunknown statusnot on this mapstarted 2023, after this paper: background citation

A Multidisciplinary Approach to Assessing and Treating Fatigue in Inflammatory Bowel Disease

TypeinterventionalSponsorUniversity College DublinRan2023 to 2025Enrolled250ConditionsInflammatory Bowel Diseases, FatigueArmsExercise Intervention, Acceptance and Commitment Therapy, Probiotic
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Sara van GennepDepartment of Gastroenterology and Hepatology, Amsterdam UMC, Amsterdam Gastroenterology and Metabolism Research Institute, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands. s.vangennep@amsterdamumc.nl.ORCID http://orcid.org/0000-0002-9843-0134
Nanne K H de BoerDepartment of Gastroenterology and Hepatology, Amsterdam UMC, Amsterdam Gastroenterology and Metabolism Research Institute, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Marieke E GielenDepartment of Gastroenterology and Hepatology, Amstelland Ziekenhuis, Amstelveen, The Netherlands.
Svend T RietdijkDepartment of Gastroenterology and Hepatology, OLVG, Amsterdam, The Netherlands.
Krisztina B GecseDepartment of Gastroenterology and Hepatology, Amsterdam UMC, Amsterdam Gastroenterology and Metabolism Research Institute, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Cyriel Y PonsioenDepartment of Gastroenterology and Hepatology, Amsterdam UMC, Amsterdam Gastroenterology and Metabolism Research Institute, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Marjolijn DuijvesteinDepartment of Gastroenterology and Hepatology, Amsterdam UMC, Amsterdam Gastroenterology and Metabolism Research Institute, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Geert R D'HaensDepartment of Gastroenterology and Hepatology, Amsterdam UMC, Amsterdam Gastroenterology and Metabolism Research Institute, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Mark LöwenbergDepartment of Gastroenterology and Hepatology, Amsterdam UMC, Amsterdam Gastroenterology and Metabolism Research Institute, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Angela G E M de BoerDepartment of Public and Occupational Health, Amsterdam UMC, Coronel Institute of Occupational Health, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.
Amsterdam University Medical Centers · NLAmsterdam Neuroscience · NLNetherlands Center for Occupational Diseases · NLOLVG · NLZiekenhuis Amstelland · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWork-related aspects are important determinants of health for inflammatory bowel disease (IBD) patients.

aimsWe aimed to describe quality of working life (QWL) in IBD patients and to assess variables that are associated with QWL.

methodsEmployed IBD patients of two tertiary and two secondary referral hospitals were included. QWL (range 0-100) was measured using the Quality of Working Life Questionnaire (QWLQ). Work productivity (WP), fatigue, and health-related quality of life (HRQL) were assessed using the Work Productivity and Activity Impairment questionnaire, Multidimensional Fatigue Inventory, and Short Inflammatory Bowel Disease Questionnaire, respectively. Active disease was defined as a score > 4 for the patient-reported Harvey-Bradshaw index in Crohn's disease (CD) or Simple Clinical Colitis Activity Index in ulcerative colitis patients.

resultsIn total, 510 IBD patients were included (59% female, 53% CD, mean age 43 (SD 12) years). The mean QWLQ score was 78 (SD 11). The lowest subscore (54 (SD 26)) was observed for "problems due to the health situation": 63% reported fatigue-related problems at work, 48% agreed being hampered at work, 46% had limited confidence in their body, and 48% felt insecure about the future due to their health situation. Intermediate/strong associations were found between QWL and fatigue (r = - 0.543, p < 0.001), HRQL (r = 0.527, p < 0.001), WP loss (r = - 0.453, p < 0.001) and disease activity (r = - 0.331, p < 0.001). Independent predictors of impaired QWL in hierarchical regression analyses were fatigue (B = - 0.204, p < 0.001), WP loss (B = - 0.070, p < 0.001), and impaired HRQL (B = 0.248, p = 0.001).

conclusionsIBD-related problems at work negatively influence QWL. Fatigue, reduced HRQL, and WP loss were independent predictors of impaired QWL in IBD.

Indexed as

Colitis, UlcerativeCrohn DiseaseEfficiencyEmployee Performance AppraisalFatigueQuality of LifeDisability EvaluationFemaleHumansMaleMiddle AgedNetherlandsPatient AcuitySeverity of Illness IndexSickness Impact ProfileSurveys and QuestionnairesFatigueInflammatory bowel diseaseJob satisfactionQuality of lifeQuality of working lifeWork performance

Identifiers

PMID33063191
PMCPMC8379106
OpenAlexW3093202595

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.