Evidence map›Paper›PMID 33063126›Full record

ReviewCellular and molecular life sciences : CMLS2021

Vault RNAs: hidden gems in RNA and protein regulation.

Jens Claus Hahne, Andrea Lampis, Nicola Valeri

Open access · hybridAbstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 64 citations in OpenAlex.

  1. The dark genome in cardiovascular medicine.European heart journal · 2026
    Review
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  12. Posttranscriptional Regulation of Intestinal Mucosal Growth and Adaptation by Noncoding RNAs in Critical Surgical Disorders.Journal of investigative surgery : the official journal of the Academy of Surgical Research · 2024
    Review
  13. The small noncoding RNARNA (New York, N.Y.) · 2024
    Article
  14. Article
  15. Review
  16. The small non-coding RNAbioRxiv : the preprint server for biology · 2024
    Article
  17. Promising predictive molecular biomarkers for cervical cancer (Review).International journal of molecular medicine · 2024
    Review
  18. Review
  19. Review
  20. Human Vault RNAs: Exploring Their Potential Role in Cellular Metabolism.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jens Claus Hahne *Division of Molecular Pathology, The Institute of Cancer Research, London, UK. Jens.Hanhe@icr.ac.uk.ORCID http://orcid.org/0000-0002-0069-0692
Andrea Lampis *Division of Molecular Pathology, The Institute of Cancer Research, London, UK.
Nicola ValeriDivision of Molecular Pathology, The Institute of Cancer Research, London, UK.
Institute of Cancer Research · GBRoyal Marsden NHS Foundation Trust · GB

Funding

Cancer Research UK 18052
6 · The paper itself

Abstract

Non-coding RNAs are important regulators of differentiation during embryogenesis as well as key players in the fine-tuning of transcription and furthermore, they control the post-transcriptional regulation of mRNAs under physiological conditions. Deregulated expression of non-coding RNAs is often identified as one major contribution in a number of pathological conditions. Non-coding RNAs are a heterogenous group of RNAs and they represent the majority of nuclear transcripts in eukaryotes. An evolutionary highly conserved sub-group of non-coding RNAs is represented by vault RNAs, named since firstly discovered as component of the largest known ribonucleoprotein complexes called "vault". Although they have been initially described 30 years ago, vault RNAs are largely unknown and their molecular role is still under investigation. In this review we will summarize the known functions of vault RNAs and their involvement in cellular mechanisms.

Indexed as

Cell DifferentiationEukaryotaGene Expression RegulationHumansProteinsRNARNA, MessengerRNA, UntranslatedTranscription FactorsProteinsRNARNA, MessengerRNA, UntranslatedTranscription FactorsNon-coding RNAsVault ribonucleoprotein complexVault RNA

Identifiers

PMID33063126
PMCPMC7904556
OpenAlexW3092655372

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.