Evidence map›Paper›PMID 33062949›Full record

ReviewACS pharmacology & translational science2020

Double-Barreled CRISPR Technology as a Novel Treatment Strategy For COVID-19.

Dhanusha A Nalawansha, Kusal T G Samarasinghe

Abstract readReview
In one paragraph

Review in ACS pharmacology & translational science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Review
  3. Immunotherapy and CRISPR Cas Systems: Potential Cure of COVID-19?Drug design, development and therapy · 2022
    Review
  4. Review
  5. Review
  6. Nano-engineered tools in the diagnosis, therapeutics, prevention, and mitigation of SARS-CoV-2.Journal of controlled release : official journal of the Controlled Release Society · 2021
    Review
  7. CRISPR/Cas-New Molecular Scissors in Diagnostics and Therapeutics of COVID-19.Indian journal of clinical biochemistry : IJCB · 2021
    Review
  8. Review
  9. Review
  10. The find of COVID-19 vaccine: Challenges and opportunities.Journal of infection and public health · 2021
    Review
  11. Review
  12. CRISPR Pioneers Win 2020 Nobel Prize for Chemistry.Iranian journal of public health · 2020
    Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dhanusha A NalawanshaDepartment of Molecular, Cellular & Developmental Biology, Yale University, New Haven, Connecticut 06511, United States.
Kusal T G SamarasingheDepartment of Molecular, Cellular & Developmental Biology, Yale University, New Haven, Connecticut 06511, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus is one of the causative agents for multiple human respiratory illnesses. A novel coronavirus, similar to the one that caused severe acute respiratory syndrome (SARS) in 2003, was identified as the cause of the current pandemic of coronavirus disease (COVID-19), which was first reported in late December 2019 in Wuhan, China. Since then, this novel coronavirus has spread across the globe, with most identified COVID-19 cases and fatalities occurring in the United States. In this Perspective, we discuss coronavirus pathogenicity, conventional antiviral therapies, prophylactic strategies, and novel treatment strategies for COVID-19. We highlight the application of CRISPR technology as an emerging pan-antiviral therapy. We also discuss the challenges of

Identifiers

PMID33062949
PMCPMC7469881

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.