Evidence map›Paper›PMID 33062934›Full record

ArticleAccess microbiology2020

Genotypic diversity, circulation patterns and co-detections among rhinoviruses in Queensland, 2001.

Katherine E Arden, Ristan M Greer, Claire Y T Wang, Ian M Mackay

Open access · goldAbstract read
In one paragraph

Article in Access microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

  1. Epidemiology and genotypic diversity of rhinovirus in school-age children with acute respiratory illnesses seeking medical care.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2025
    Article
  2. Article
  3. Article
  4. SARS-CoV-2 infection in children in Moscow in 2020: clinical features and impact on circulation of other respiratory viruses: SARS-CoV-2 infection in children in Moscow in 2020.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
    Article
  5. Viral Interference between Respiratory Viruses.Emerging infectious diseases · 2022
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. First contact: the role of respiratory cilia in host-pathogen interactions in the airways.American journal of physiology. Lung cellular and molecular physiology · 2020
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Katherine E ArdenChild Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.ORCID https://orcid.org/0000-0003-3195-124X
Ristan M GreerFaculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.ORCID https://orcid.org/0000-0002-1574-4729
Claire Y T WangChild Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.
Ian M MackayChild Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.ORCID https://orcid.org/0000-0003-3598-2350
The University of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRhinoviruses (RVs) occur more frequently than other viruses and more often in people displaying symptoms than in those without. We sought to estimate the spectrum of RV diversity, RV species seasonality and to analyse RV involvement in respiratory virus co-detections. METHODOLOGY: A convenience collection of 1179 airway sample extracts from patients with suspected respiratory infections, collected during 2001, was subjected to comprehensive molecular testing.

resultsRVs were the most common virus detected. We were able to genotype ~90 % of RV detections, identifying 70 distinct RVs, spanning all three species. RV-Bs were under-represented. We found RV species co-circulated at times, although one species usually dominated. Each species displayed a bimodal distribution.

conclusionNotably, RVs and influenza A viruses (IFAV) seldom co-occurred, supporting their roles as primary pathogens of the airway among acutely ill infants. Whether RV circulation has a moderating or controlling effect on the IFAV season or is controlled by it cannot be determined from these data. Despite the frequent perception that RVs commonly co-occur with another virus, our findings indicated this was not always the case. Nearly 80 % of RV detections occurred alone. Understanding more about population-level interference between viruses may allow us to harness aspects of it to generate a non-specific antiviral intervention that mimics a putative protective effect. For routine respiratory virus screening to best serve the patient, RV testing should be a principal component of any acute respiratory illness testing algorithm throughout the year.

Indexed as

diagnosticsepidemiologyprevalenceRhinovirusRVvirus interactions

Identifiers

PMID33062934
PMCPMC7525053
OpenAlexW2988506773

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.