ArticleInternational journal of reproductive biomedicine2020
Effect of Zirconium oxide nanoparticle on serum level of testosterone and spermatogenesis in the rat: An experimental study.
Article in International journal of reproductive biomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed, 6 citations in OpenAlex.
- Article
- Advances of plant and biomass extracted zirconium nanoparticles in dental implant application.Heliyon · 2023Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundZirconium nanoparticles are used as health agents, pharmaceutical carriers, and in dental and orthopedic implants.
objectiveThis studyaimed to investigate the effects of Zirconium oxide nanoparticles on the process of spermatogenesis in rat. MATERIALS AND
methodsIn this experimental study, 32 male Wistar rats (150-200 gr), with range of age 2.5 to 3 months were used and divided into four groups of eight per each. The control group received 0.5 ml of distilled water and the three experimental groups received 50, 200, and 400 ppm doses of Zirconium oxide nanoparticles solution over a 30-day period, respectively. At the end of the experiment, tissue sections were taken from the testis and stained with hematoxylin-eosin. Serum concentration of testosterone was measured by enzyme-linked immunosorbent assay.
resultsIn the experimental group receiving 400 ppm Zirconium oxide nanoparticles, the number of Spermatogonia cells (p
conclusionZirconium oxide nanoparticles are likely to damage the testes by increasing Reactive oxygen species production and free radicals.
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Registered trials
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