Evidence map›Paper›PMID 33062920›Full record

ArticleInternational journal of reproductive biomedicine2020

Role of the 820 A/G variant in the

Farzaneh Ardeshir, Leila Keshavarz, Fatemeh Asadian, Gohar Omidmokhtarkhanloo, Majid Yavarian

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of reproductive biomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Farzaneh ArdeshirDepartment of Biology, Islamic Azad University, Arsanjan Branch, Arsanjan, Iran.
Leila KeshavarzDepartment of Biology, Islamic Azad University, Arsanjan Branch, Arsanjan, Iran.
Fatemeh AsadianDepartment of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran.
Gohar OmidmokhtarkhanlooDepartment of Biology, Islamic Azad University, Arsanjan Branch, Arsanjan, Iran.
Majid YavarianPersian Bayan Gene Research and Training Center, Dr. Faghihi's Medical Genetic Center, Siraz, Iran.
Islamic Azad University of Arsanjan · IRShiraz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInsulin-like growth factor-2 (

objectiveThis cross-sectional study aimed to investigate the role of 820A/G variant of the MATERIALS AND

methodsIn this study, 50 aborted fetuses tissue for the study group and blood samples umbilical-cord from newborns as control group (n = 50) were collected from Shiraz-Iran (2017). The genotyping of the target point in the

resultsBased on the collected data (AA genotype = reference), allele "A" frequency in aborted fetus was 51% and control 68% as well as allele G 49% and 32%, respectively. Moreover, 27 aborted embryos (54%) were heterozygous (A/G) (OR = 3.274, 95% CI = 1.015-10.561, p = 0.04), while 18 cases (36%) in control sample showed heterozygosity. Considering the phenotypic status, the G allele had a dominant effect on the incidence of RSA (p = 0.008, OR = 3.167).

conclusionBased on the present study, the risk of abortion due to loss of heterozygosity or quantitative decline of the

Indexed as

Gene expressionGenomic imprintingIGF-2Spontaneous abortionVariant

Identifiers

PMID33062920
PMCPMC7521167
OpenAlexW3089258477

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.