Evidence map›Paper›PMID 33062689›Full record

ArticleBioMed research international2020

Machine Learning-Based Differentiation of Nontuberculous Mycobacteria Lung Disease and Pulmonary Tuberculosis Using CT Images.

Zhiheng Xing, Wenlong Ding, Shuo Zhang, Lingshan Zhong, Li Wang, Jigang Wang, Kai Wang, Yi Xie, Xinqian Zhao, Nan Li and 1 more

Abstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhiheng XingTianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin's Clinical Research Center for Cancer, Tianjin, China.
Wenlong DingHaihe Hospital, Tianjin University, Tianjin Institute of Respiratory Diseases, Tianjin, China.
Shuo ZhangHaihe Hospital, Tianjin University, Tianjin Institute of Respiratory Diseases, Tianjin, China.
Lingshan ZhongHaihe Hospital, Tianjin University, Tianjin Institute of Respiratory Diseases, Tianjin, China.
Li WangHaihe Hospital, Tianjin University, Tianjin Institute of Respiratory Diseases, Tianjin, China.
Jigang WangHaihe Hospital, Tianjin University, Tianjin Institute of Respiratory Diseases, Tianjin, China.
Kai WangHaihe Hospital, Tianjin University, Tianjin Institute of Respiratory Diseases, Tianjin, China.
Yi XieHaihe Hospital, Tianjin University, Tianjin Institute of Respiratory Diseases, Tianjin, China.
Xinqian ZhaoHaihe Hospital, Tianjin University, Tianjin Institute of Respiratory Diseases, Tianjin, China.
Nan LiHaihe Hospital, Tianjin University, Tianjin Institute of Respiratory Diseases, Tianjin, China.
Zhaoxiang YeTianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin's Clinical Research Center for Cancer, Tianjin, China.ORCID https://orcid.org/0000-0003-3157-8393

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An increasing number of patients infected with nontuberculous mycobacteria (NTM) are observed worldwide. However, it is challenging to identify NTM lung diseases from pulmonary tuberculosis (PTB) due to considerable overlap in classic manifestations and clinical and radiographic characteristics. This study quantifies both cavitary and bronchiectasis regions in CT images and explores a machine learning approach for the differentiation of NTM lung diseases and PTB. It involves 116 patients and 103 quantitative features. After the selection of informative features, a linear support vector machine performs disease classification, and simultaneously, discriminative features are recognized. Experimental results indicate that bronchiectasis is relatively more informative, and two features are figured out due to promising prediction performance (area under the curve, 0.84 ± 0.06; accuracy, 0.85 ± 0.06; sensitivity, 0.88 ± 0.07; and specificity, 0.80 ± 0.12). This study provides insight into machine learning-based identification of NTM lung diseases from PTB, and more importantly, it makes early and quick diagnosis of NTM lung diseases possible that can facilitate lung disease management and treatment planning.

Indexed as

Machine LearningAdultAgedBronchiectasisFemaleHumansImage Interpretation, Computer-AssistedLungMaleMiddle AgedMycobacterium Infections, NontuberculousNontuberculous MycobacteriaSensitivity and SpecificityTomography, X-Ray ComputedTuberculosis, Pulmonary

Identifiers

PMID33062689
PMCPMC7545409

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.