Evidence map›Paper›PMID 33062684›Full record

ArticleBioMed research international2020

2-Methacryloyloxyethyl Phosphorylcholine Polymer Coating Inhibits Bacterial Adhesion and Biofilm Formation on a Suture: An

Taizo Kaneko, Taku Saito, Takeo Shobuike, Hiroshi Miyamoto, Junpei Matsuda, Kyoko Fukazawa, Kazuhiko Ishihara, Sakae Tanaka, Toru Moro

Abstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Biomimetic polymers with phosphorylcholine groups as biomaterials for medical devices.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2024
    Review
  2. Comparative Evaluation ofVision (Basel, Switzerland) · 2023
    Article
  3. Article
  4. Evaluation ofMicroorganisms · 2023
    Article
  5. Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Taizo KanekoSensory & Motor System Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.
Taku SaitoSensory & Motor System Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.
Takeo ShobuikeSensory Department of Pathology and Microbiology, Faculty of Medicine, Saga University, Saga 849-8501, Japan.
Hiroshi MiyamotoSensory Department of Pathology and Microbiology, Faculty of Medicine, Saga University, Saga 849-8501, Japan.
Junpei MatsudaProject Management Department, KEISEI Medical Industrial Corporation Limited, 3-19-6, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Kyoko FukazawaDepartment of Materials Engineering, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.
Kazuhiko IshiharaDepartment of Materials Engineering, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.
Sakae TanakaSensory & Motor System Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.ORCID https://orcid.org/0000-0001-9210-9414
Toru MoroSensory & Motor System Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.ORCID https://orcid.org/0000-0002-7448-5237

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Initial bacterial adhesion to medical devices and subsequent biofilm formation are known as the leading causes of surgical site infection (SSI). Therefore, inhibition of bacterial adhesion and biofilm formation on the surface of medical devices can reduce the risk of SSIs. In this study, a highly hydrophilic, antibiofouling surface was prepared by coating the bioabsorbable suture surface with poly(2-methacryloyloxyethyl phosphorylcholine (MPC)-co-n-butyl methacrylate) (PMB). The PMB-coated and noncoated sutures exhibited similar mechanical strength and surface morphology. The effectiveness of the PMB coating on the suture to suppress adhesion and biofilm formation of methicillin-resistant

Indexed as

AnimalsAnti-Bacterial AgentsBacterial AdhesionBiofilmsCoated Materials, BiocompatibleMaleMethacrylatesMethicillin-Resistant Staphylococcus aureusMiceMice, Inbred C57BLPhosphorylcholineStaphylococcus aureusSutures2-methacryloyloxyethyl phosphorylcholineAnti-Bacterial AgentsCoated Materials, BiocompatibleMethacrylatesPhosphorylcholine

Identifiers

PMID33062684
PMCPMC7547360

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.