Evidence map›Paper›PMID 33062628›Full record

ArticleTranslational and clinical pharmacology2020

Qualification and application of liquid chromatography-quadrupole time-of-flight mass spectrometric method for the determination of carisbamate in rat plasma and prediction of its human pharmacokinetics using physiologically based pharmacokinetic modeling.

Byeong Ill Lee, Jeong-Hyeon Lim, Min-Ho Park, Seok-Ho Shin, Jin-Ju Byeon, Jang-Mi Choi, Seo-Jin Park, Min-Jae Park, Yuri Park, Young G Shin

Abstract read
In one paragraph

Article in Translational and clinical pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Byeong Ill LeeCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Jeong-Hyeon LimCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Min-Ho ParkCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Seok-Ho ShinCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Jin-Ju ByeonCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Jang-Mi ChoiCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Seo-Jin ParkCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Min-Jae ParkCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Yuri ParkCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Young G ShinCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.ORCID https://orcid.org/0000-0002-7135-8988

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carisbamate is an antiepileptic drug and it also has broad neuroprotective activity and anticonvulsant reaction. In this study, a liquid chromatography-quadrupole time-of-flight mass spectrometric (LC-qTOF-MS) method was developed and applied for the determination of carisbamate in rat plasma to support

Indexed as

CarisbamateLC-MSPBPK ModelingQualification

Identifiers

PMID33062628
PMCPMC7533164

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.