ArticleClinical nephrology. Case studies2020
Brown tumor complicating end-stage kidney disease.
Article in Clinical nephrology. Case studies, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Article
- Multiple spinal brown tumors presenting as compressive thoracic myelopathy in a patient on maintenance hemodialysis.Journal of surgical case reports · 2025Article
- Article
- Extravertebral low back pain: a scoping review.BMC musculoskeletal disorders · 2024Article
- Calcified Maxillary Fibroma in a Patient on Hemodialysis for Seven Years.European journal of case reports in internal medicine · 2024Article
- Brown Tumour in Chronic Kidney Disease: Revisiting an Old Disease with a New Perspective.Cancers · 2023Review
- Article
- A rare case of "Brown tumor" of the axis with parathyroid adenoma and tertiary hyperparathyroidism.Journal of craniovertebral junction & spineArticle
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Authors and funding
1 author.
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Abstract
Longstanding, severe hyperparathyroidism (HPT) can lead to the formation of "brown tumors". A brown tumor is a radiolucent bone lesion that is locally destructive; it is not a neoplasm, but rather a stromal mass consisting of fibrous tissue, poorly mineralized woven bone, and supporting vasculature. These tumors are a rare complication of advanced primary or secondary HPT. We present a young female with chronic kidney disease (CKD) on hemodialysis with uncontrolled secondary HPT (SHPT). The patient presented with progressive lower extremity weakness and back pain. CT imaging showed multiple lytic bone lesions involving several ribs and the spine. Subsequent MRI imaging of the thoracic and lumbar spine confirmed expansile bone lesions consistent with brown tumors. One mass protruded into the spinal canal causing severe stenosis at T3 with underlying cord edema. The other lesion at T12 caused only moderate spinal canal stenosis. Our patient underwent urgent neurosurgical resection of the tumor at T3 followed by subtotal parathyroidectomy (PTX).
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