ArticleJournal of animal science and biotechnology2020
Dietary L-citrulline supplementation modulates nitric oxide synthesis and anti-oxidant status of laying hens during summer season.
Article in Journal of animal science and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 36 citations in OpenAlex.
- The Effects of Arginine, Guanidinoacetic Acid and Citrulline Supplementation to Reduced Protein Diets for Aged Laying Hens.Animals : an open access journal from MDPI · 2026Article
- Effect of L-citrulline injection on testicular hemodynamics and semen quality in aged bucks.Veterinary research communications · 2026Article
- Respiratory efficiency and thermoregulatory responses of L-citrulline-supplemented broiler chickens under acute and chronic stress conditions.Frontiers in physiology · 2026Article
- Increasing arginine supplementation alleviated heat stress and citrulline can effectively substitute arginine in broilers.Journal of animal science and technology · 2026Article
- Effects of inulin on growth performance and intestinal health of broilers by modulating intestinal microbiota and metabolome.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Article
- Dietary supplementation withFrontiers in microbiology · 2025Article
- Guanidinoacetic acid supplementation and stocking density effects on broiler performance: behavior, biochemistry, immunity, and small intestinal histomorphology.Acta veterinaria Scandinavica · 2024Article
- Effects of supplemental citrulline on thermal and intestinal morphology parameters during heat stress and feed restriction in growing pigs.Journal of animal science · 2024Article
- High-altitude and low-altitude adapted chicken gut-microbes have different functional diversity.Scientific reports · 2023Article
- Effects of arginine replacement with L-citrulline on the arginine/nitric oxide metabolism in chickens: An animal model without urea cycle.Journal of animal science and biotechnology · 2023Article
- Beyond protein synthesis: the emerging role of arginine in poultry nutrition and host-microbe interactions.Frontiers in physiology · 2023Review
- Functional roles of taurine, L-theanine, L-citrulline, and betaine during heat stress in poultry.Journal of animal science and biotechnology · 2022Review
- Dietary L-citrulline modulates the growth performance, amino acid profile, and the growth hormone/insulin-like growth factor axis in broilers exposed to high temperature.Frontiers in physiology · 2022Article
- Ultra-Performance Liquid Chromatography-Mass Spectrometry-Based Untargeted Metabolomics Reveals the Key Potential Biomarkers for Castor Meal-Induced Enteritis in Juvenile Hybrid Grouper (Frontiers in nutrition · 2022Article
- Natural Products of Plants and Animal Origin Improve Albumen Quality of Chicken Eggs.Frontiers in nutrition · 2022Review
- Potential Implications of Citrulline and Quercetin on Gut Functioning of Monogastric Animals and Humans: A Comprehensive Review.Nutrients · 2021Review
- Response of laying hens to l-arginine, l-citrulline and guanidinoacetic acid supplementation in reduced protein diet.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2021Article
- L-Citrulline Influences the Body Temperature, Heat Shock Response and Nitric Oxide Regeneration of Broilers Under Thermoneutral and Heat Stress Condition.Frontiers in physiology · 2021Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundL-citrulline (L-Cit), a non-protein amino acid, has been implicated in several physiological functions including anti-inflammatory, anti-oxidative, and hypothermic roles, however, there is a paucity of information with regards to its potential in poultry production.
methodsThis study was designed to investigate the effects of dietary L-Cit supplementation on the production performance, nitric oxide production, and antioxidant status of laying hens during summer period. Hy-Line Brown laying hens (
resultsAir temperature monitoring indicated an average daily minimum and maximum temperatures of 25.02 °C and 31.01 °C respectively. Dietary supplementation with L-Cit did not influence (
conclusionDietary L-Cit supplementation modulated systemic arginine metabolism, nitric oxide synthesis, antioxidant defense system, and increased the egg shape index of laying hens during the summer season. 1% L-Cit supplementation proved most effective in potentiating these effects and may be adopted for feed formulation strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.