Evidence map›Paper›PMID 33062137›Full record

ArticleOxidative medicine and cellular longevity2020

Isokotomolide A from Cinnamomum kotoense Induce Melanoma Autophagy and Apoptosis

Jian Li, Chung-Yi Chen, Jyun Yin Huang, Lin Wang, Zixuan Xu, Wenyi Kang, Miao-Hsia Lin, Hui-Min David Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Antioxidants (Basel, Switzerland) · 2022
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jian LiCollege of Food and Biological Engineering, Jimei University, Xiamen 361021, China.
Chung-Yi ChenDepartment of Nutrition and Health Science, School of Medical and Health Sciences, Fooyin University, Kaohsiung 831, Taiwan.
Jyun Yin HuangGraduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung 402, Taiwan.
Lin WangCollege of Chemistry & Pharmacy, Northwest A&F University, Yangling, Shaanxi 712100, China.
Zixuan XuCollege of Food and Biological Engineering, Jimei University, Xiamen 361021, China.
Wenyi KangJoint International Research Laboratory of Food & Medicine Resource Function, Henan Province, Henan University, Kaifeng 475004, China.
Miao-Hsia LinGraduate Institute of Microbiology, College of Medicine National Taiwan University, Taipei 100, Taiwan.
Hui-Min David WangCollege of Food and Biological Engineering, Jimei University, Xiamen 361021, China.ORCID https://orcid.org/0000-0002-4692-4917

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melanoma is an aggressive cancer with high lethality. In order to find new anticancer agents, isokotomolide A (Iso A) and secokotomolide A (Sec A) isolated from

Indexed as

4-ButyrolactoneAlkanesAnimalsApoptosisAutophagyBeclin-1Caspase 9Cell Cycle CheckpointsCell Line, TumorCell ProliferationCinnamomumDNA DamageFemaleMelanomaMiceMice, Nude4-ButyrolactoneAlkanesBeclin-1Caspase 9kotomolide Asecokotomolide A

Identifiers

PMID33062137
PMCPMC7537700

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.