ReviewAnnals of general psychiatry2020
How to improve adherence to antidepressant treatments in patients with major depression: a psychoeducational consensus checklist.
Review in Annals of general psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Development, Feasibility, and Appreciation of the Collaborative Integrated Depression Care (IDECA) Project in Flanders, Belgium.Journal of clinical medicine · 2026Article
- A Quasi-Experimental Evaluation of a Primary Care Behavioral Health Integration Program Based on the Chronic Care Model.Journal of general internal medicine · 2026Observational
- The Decision-Making Process of Antidepressant Use Among Patients with Depression: A Grounded Theory Study.Patient preference and adherence · 2026Article
- The effectiveness of a multi-dimensional intervention model combining cognitive behavioral therapy and social support in hospitalized depressed patients.BMC psychiatry · 2025Article
- Practices, attitudes, and perceived barriers toward depression care among community pharmacists in Lebanon.Journal of public health research · 2025Article
- Nurse-led inpatient education using a gamification approach for patients with mental illness: A quasi-experimental study.International journal of nursing sciences · 2025Article
- Probing Public Perceptions of Antidepressants on Social Media: Mixed Methods Study.JMIR formative research · 2025Article
- Trajectories of antidepressant use after tamoxifen initiation among young and middle-aged women with breast cancer.Breast cancer research and treatment · 2025Article
- Affective Temperaments and Seasonality in Patients with Mood Disorders.Neuropsychiatric disease and treatment · 2025Article
- Context Factors Associated with Medication Adherence Among Thai Adolescents with Major Depressive Disorder.Patient preference and adherence · 2025Article
- The short-term effectiveness of antidepressants in a transdiagnostic sample and determinants of side effects and medication nonadherence: an observational study.Frontiers in psychiatry · 2025Article
- A Multi-Center, Open-Label, Single-Arm Study to Investigate the Early Effectiveness of Esketamine Nasal Spray in Patients with Treatment-Resistant Depression Using a Mobile Self-Monitoring Application.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Impact of trazodone once-a-day on quality of life and functional recovery in adults with major depressive disorder: A prospective, observational study.Brain and behavior · 2024Observational
- The Dropout Rates and Associated Factors in Patients with Mood Disorders in Long-term Naturalistic Treatment.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2024Article
- Looking through the lens of stigma: Understanding and anticipating concerns about the responsible development and use of psychiatric electroceutical interventions (PEIs).SSM. Mental health · 2023Article
- Improving the Therapeutic Relationship When Prescribing Antidepressants: A Pilot Study.Healthcare (Basel, Switzerland) · 2023Article
- Reasons for Discontinuation or Change of Selective Serotonin Reuptake Inhibitors in Online Drug Reviews.JAMA network open · 2023Article
- Knowledge and attitudes on medication adherence and residual symptoms in individuals with depression: a survey at a University Hospital.BMC psychiatry · 2023Article
- Overcoming treatment gaps in the management of depression with non-pharmacological adjunctive strategies.Frontiers in psychiatry · 2023Review
- Physical activity influences adherence to pharmacological treatments in patients with severe mental disorders: results from the multicentric, randomized controlled LIFESTYLE trial.Frontiers in pharmacology · 2023Article
Corrections and comments
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies conducted in primary care as well as in psychiatric settings show that more than half of patients suffering from major depressive disorder (MDD) have poor adherence to antidepressants. Patients prematurely discontinue antidepressant therapy for various reasons, including patient-related (e.g., misperceptions about antidepressants, side-effects, and lack of tolerability), clinician-related (e.g., insufficient instruction received by clinicians about the medication, lack of shared decision-making, and follow-up care), as well as structural factors (e.g., access, cost, and stigma). The high rate of poor adherence to antidepressant treatments provides the impetus for identifying factors that are contributing to noncompliance in an individual patient, to implement a careful education about this phenomenon. As adherence to antidepressants is one of the major unmet needs in MDD treatment, being associated with negative outcomes, we sought to identify a series of priorities to be discussed with persons with MDD with the larger aim to improve treatment adherence. To do so, we analyzed a series of epidemiological findings and clinical reasons for this phenomenon, and then proceeded to define through a multi-step consensus a set of recommendations to be provided by psychiatrists and other practitioners at the time of the first (prescription) visit with patients. Herein, we report the results of this initiative.
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