Evidence map›Paper›PMID 33061938›Full record

ArticleFrontiers in genetics2020

The m6A Methyltransferase METTL3 Is Functionally Implicated in DLBCL Development by Regulating m6A Modification in PEDF.

Yingying Cheng, Yuanyuan Fu, Ying Wang, Jinbi Wang

Abstract read
In one paragraph

Article in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. METTL3-dependent mJournal of translational medicine · 2026
    Article
  3. Regulation of mCell biology and toxicology · 2026
    Review
  4. Review
  5. Targeting intracellular mRNA mJournal of advanced research · 2026
    Review
  6. Review
  7. Article
  8. Article
  9. NMolecular medicine (Cambridge, Mass.) · 2024
    Review
  10. Review
  11. Article
  12. Methylation of T and B Lymphocytes in Autoimmune Rheumatic Diseases.Clinical reviews in allergy & immunology · 2024
    Review
  13. Review
  14. Article
  15. Review
  16. Exploring the impact of mFrontiers in immunology · 2024
    Review
  17. The role of mGenes & diseases · 2024
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yingying ChengDepartment of Hematology, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, Luoyang, China.
Yuanyuan FuDepartment of Hematology, Changzhou Traditional Chinese Medicine Hospital, Changzhou, China.
Ying WangDepartment of Hematology, Changzhou Traditional Chinese Medicine Hospital, Changzhou, China.
Jinbi WangDepartment of Hematology, Changzhou Traditional Chinese Medicine Hospital, Changzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of lymphoma, whose treatment still has a major challenge of achieving a satisfactory curative effect. The underlying mechanisms also have not been fully illustrated.

Indexed as

DLBCLMETTL3N6-methyladenosinePEDFproliferation

Identifiers

PMID33061938
PMCPMC7481464

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.