ArticleFood & nutrition research2020
Marine fish peptides (collagen peptides) compound intake promotes wound healing in rats after cesarean section.
Article in Food & nutrition research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 23 citations in OpenAlex.
- Multifaceted Marine Peptides and Their Therapeutic Potential.Marine drugs · 2025Review
- Perch Hydrolysates from Upcycling of Perch Side Streams Accelerate Wound Healing by Enhancing Fibroblasts to Secrete Procollagen I, Fibronectin, and Hyaluronan.Current issues in molecular biology · 2025Article
- Immortelle Essential-Oil-Enriched Hydrogel for Diabetic Wound Repair: Development, Characterization, and In Vivo Efficacy Assessment.Pharmaceutics · 2024Article
- Toxicity of a 90-day repeated oral dose of a collagen peptide derived from skate (Toxicological research · 2023Article
- Food-derived bioactive oligopeptide iron complexes ameliorate iron deficiency anemia and offspring development in pregnant rats.Frontiers in nutrition · 2022Article
- Formulation and Evaluation ofPharmaceuticals (Basel, Switzerland) · 2021Article
- Collagen-Containing Fish Sidestream-Derived Protein Hydrolysates Support Skin Repair via Chemokine Induction.Marine drugs · 2021Article
- Marine-Derived Collagen as Biomaterials for Human Health.Frontiers in nutrition · 2021Review
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWound complications are a major source of morbidity after cesarean section (CS) and contribute to increased risks in subsequent pregnancies. In the present study, we aim to investigate the wound healing potential of a kind of oligopeptide compound, mainly derived from the marine fish peptides (MFPs), in rats after CS by biomechanical, biochemical, and histological methods.
methodsEighty-four pregnant Sprague-Dawleyrats were randomly assigned to four groups, namely the control group and 1.1, 2.2, and 4.4 mg/kg MFP groups, respectively. The MFPs or normal saline of the equal volume was intragastrically administered every morning on the second day after CS. On days 5, 10, and 15 after the surgery, seven rats from each group were randomly selected. The samples of skin wound and uterus were harvested and then used for the following experiments and analyses.
resultsUsing the CS rat model, this study demonstrated that in the MFP groups, the skin tensile strength, uterine bursting pressure, and hydroxyproline (Hyp) were significantly higher than those in the control group at all three time points (
conclusionsMFPs have a great potential to accelerate the process and quality of wound healing in rats after CS.
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