Evidence map›Paper›PMID 33061753›Full record

ArticleTurk pediatri arsivi2020

The danger awaiting premature babies: Portal vein thrombosis.

Salih Çağrı Çakır, Hilal Özkan, Bayram Ali Dorum, Nilgün Köksal, Pınar Kudretoğlu, Birol Baytan, Melike Sezgin, Adalet Meral Güneş

Open access · greenAbstract read
In one paragraph

Article in Turk pediatri arsivi, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Extrahepatic Portal Vein Thrombosis in Childhood: Risk Factors, Clinical Manifestations, and Management.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2022
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Salih Çağrı ÇakırDivision of Neonatology, Department of Pediatrics, Uludağ University Faculty of Medicine, Bursa, Turkey.
Hilal ÖzkanDivision of Neonatology, Department of Pediatrics, Uludağ University Faculty of Medicine, Bursa, Turkey.
Bayram Ali DorumDivision of Neonatology, Department of Pediatrics, Uludağ University Faculty of Medicine, Bursa, Turkey.
Nilgün KöksalDivision of Neonatology, Department of Pediatrics, Uludağ University Faculty of Medicine, Bursa, Turkey.
Pınar KudretoğluDepartment of Pediatrics, Uludağ University Faculty of Medicine, Bursa, Turkey.
Birol BaytanDivision of Pediatric Hematology, Department of Pediatrics, Uludağ University Faculty of Medicine, Bursa, Turkey.
Melike SezginDivision of Pediatric Hematology, Department of Pediatrics, Uludağ University Faculty of Medicine, Bursa, Turkey.
Adalet Meral GüneşDivision of Pediatric Hematology, Department of Pediatrics, Uludağ University Faculty of Medicine, Bursa, Turkey.
Bursa Uludağ Üni̇versi̇tesi̇ · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimUmbilical venous catheters are frequently used in the neonatal period. The incidence of umbilical venous catheter-related thrombosis is between 1.3% and 43% in ultrasound scans. This study aimed to determine the incidence and risk of portal vein thrombosis in patients who were hospitalized in the neonatal intensive care unit and underwent umbilical venous catheter insertion. MATERIAL AND

methodsPremature infants (≤32 gestational weeks) who were hospitalized in a Level III neonatal intensive care unit and underwent umbilical vein catheter placement between 2016 and 2018, were included in the study. The demographic data, clinical risk factors for thrombosis, number of catheter days, catheter locations, times of detection of thrombosis using Doppler ultrasonography, treatment methods and durations, thrombosis follow-up and examinations were obtained retrospectively from the electronic patient files.

resultsNinety-six patients whose complete data could be reached were enrolled in the study. The mean gestational age of the patients was found as 29±2 weeks and the mean birth weight was 1353±369 g. Portal vein thrombosis was detected in 13.5% (n=13) of the patients. Five of the cases of portal vein thrombose were complete occlusion and eight were partial occlusion. All patients with complete occlusion and six patients with partial occlusion were treated with low-molecular-weight heparin for a mean duration of 31±13.8 days. Thrombosis disappeared in 7-120 days in all patients. A thrombophilia mutation was detected in six patients with thrombosis, four of whom had the PAI-1 4G / 5G mutation.

conclusionPortal vein thrombosis which has a significant place among the causes of portal hypertension in childhood, is mostly asymptomatic in the neonatal period and cannot be recognized clinically. It is important to screen and follow up patients with umbilical vein catheters using Doppler ultrasonography in terms of PVT after catheter removal to prevent long-term complications.

Indexed as

Newbornportal vein thrombosisprematureumbilical vein catheter

Identifiers

PMID33061753
PMCPMC7536447
OpenAlexW3019633190

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.