ArticleClinical pharmacology : advances and applications2020
Hypoglycemic and Antihyperglycemic Activities of 80% Methanol Root Extract of
Article in Clinical pharmacology : advances and applications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 8 citations in OpenAlex.
- Article
- Evaluation of the anti-hyperglycemic and anti-dyslipidemic potential of the hydroethanolic extract ofMetabolism open · 2026Article
- Article
- Evaluation of the Antidiabetic Potential of Xanthone-Rich Extracts fromInternational journal of molecular sciences · 2024Article
- Pharmacological evaluation of medicinal plants with antidiabetic activities in Ethiopia: A review.Metabolism open · 2022Review
- Effects of the Oral Administration of Aqueous and Methanolic Leaf Extracts ofJournal of experimental pharmacology · 2022Article
- Antidiabetic Activity of Hydromethanolic Extract of CrudeJournal of experimental pharmacology · 2022Article
- Medicinal Plant Extracts EvaluatedEvidence-based complementary and alternative medicine : eCAM · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe morbidity and mortality rate from diabetic mellitus are increasing in the world especially in low- and middle-income countries; hence, it is necessary to evaluate the efficacy and safety of medicinal plants to support existing drugs in treating diabetes mellitus. Therefore, the aim of this study was to evaluate the hypoglycemic effect of 80% methanol root extract of
methodsMale albino Wistar rats were divided into five groups (n=6) in all three models. In all models, group one rats served as a negative control and were received vehicle (10mL/kg distilled water), whereas group two (APRE100), three (APRE200), and four (APRE400) were treated with 100, 200, and 400mg/kg of extract, respectively, and group five were treated with glibenclamide (5mg/kg) and served as a positive control. Blood glucose levels were measured at different time points by taking blood from their tails. Data were analyzed using one-way ANOVA followed by Tukey's post hoc test to carry out comparisons between and within-group and P < 0.05 was considered as statistically significant.
resultsThe root of
conclusionFrom this study, it can be concluded that the root extract of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.