Evidence map›Paper›PMID 33061572›Full record

ArticleCancer management and research2020

Knockdown of MIR4435-2HG Suppresses the Proliferation, Migration and Invasion of Cervical Cancer Cells via Regulating the miR-128-3p/MSI2 Axis in vitro.

Ruijing Wang, Lun Liu, Jinwen Jiao, Dongmei Gao

Open access · goldAbstract read
In one paragraph

Article in Cancer management and research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ruijing WangDepartment of Gynecology, The Affiliated Hospital of Qingdao University, Qingdao City, Shandong Province 266555, People's Republic of China.
Lun LiuDepartment of Surgery, The Affiliated Hospital of Qingdao University, Qingdao City, Shandong Province 266555, People's Republic of China.
Jinwen JiaoDepartment of Gynecology, The Affiliated Hospital of Qingdao University, Qingdao City, Shandong Province 266555, People's Republic of China.
Dongmei GaoDepartment of Gynecology, The Affiliated Hospital of Qingdao University, Qingdao City, Shandong Province 266555, People's Republic of China.
Qingdao University · CNAffiliated Hospital of Qingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLong non-coding RNAs (lncRNAs) play major roles in the development of several cancers, including cervical cancer (CC). The purpose of the present study is to explore the regulatory mechanism of MIR4435-2HG on CC in vitro. PATIENTS AND

methodsFifty-nine pairs of CC tissues and adjacent normal tissues were collected from 59 patients by resection. The expression of lncRNA MIR4435-2HG, microRNA (miR)-128-3p and

resultsLncRNA MIR4435-2HG expression was significantly up-regulated in CC tissues (

conclusionMIR4435-2HG knockdown suppresses the proliferation, migration and invasion of CC cells through regulating the miR-128-3p/

Indexed as

cervical cancerlncRNA MIR4435-2HGmiR-128-3pMSI2

Identifiers

PMID33061572
PMCPMC7519841
OpenAlexW3087097754

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.