ArticleCancer management and research2020
The Predictive Value of MLR for Radiation Pneumonia During Radiotherapy of Thoracic Tumor Patients.
Article in Cancer management and research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed.
- Integrated machine learning risk model for predicting radiation pneumonitis in lung cancer patients with interstitial lung disease.Annals of medicine · 2026Article
- An explainable nomogram incorporating systemic inflammatory indicators and radiation esophagitis for risk assessment of radiation pneumonitis in lung cancer.Frontiers in immunology · 2026Article
- Time-of-day radiotherapy alters radiation pneumonitis risk but not survival in lung cancer patients with interstitial lung disease.Therapeutic advances in medical oncology · 2026Article
- Dynamic monocyte changes as prognostic indicators in operable gastric cancer: a retrospective cohort analysis.Frontiers in oncology · 2025Article
- Predictive significance of the hemoglobin, albumin, lymphocyte, and platelet score for radiation pneumonitis in lung cancer patients: a respective comparative study with dosimetric parameters.Frontiers in oncology · 2025Article
- Derived neutrophil-to-lymphocyte ratio has the potential to predict safety and outcomes of durvalumab after chemoradiation in non-small cell lung cancer.Scientific reports · 2024Article
- Predicting the prognosis of operable gastric cancer patients by dynamic changes in platelets before and after surgery: a retrospective cohort study.Journal of cancer research and clinical oncology · 2023Article
- Radiation pneumonia predictive model for radiotherapy in esophageal carcinoma patients.BMC cancer · 2023Article
- A multiomics approach-based prediction of radiation pneumonia in lung cancer patients: impact on survival outcome.Journal of cancer research and clinical oncology · 2023Article
- Construction and Verification of a Radiation Pneumonia Prediction Model Based on Multiple Parameters.Cancer control : journal of the Moffitt Cancer CenterArticle
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10 authors.
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Abstract
purposeTo evaluate the predictive value of blood lymphocyte, monocyte to lymphocyte ratio (MLR), and neutrophil to lymphocyte ratio (NLR) for radiation pneumonia (RP) in patients with thoracic tumors receiving radiotherapy. PATIENTS AND
methodsThe clinical data of 65 patients with thoracic tumor (esophageal cancer, lung cancer) treated by radiotherapy in our hospital were retrospectively analyzed. Patients were divided into the RP group and the non-RP group according to the Common Terminology Criteria for Adverse Events (CTCAE 5.0). Data on blood cell counts, including lymphocytes, monocytes, and neutrophils, were collected before (0 weeks) and after 1, 2, and 4 weeks of radiotherapy.
resultsOf the 65 patients enrolled, 27 developed radiation pneumonia and 38 did not. Patients' clinical factors, including age, TNM stage, tumor type, underlying lung disease, and history of smoking, had no correlation with RP. ANOVA of repeated measurement data showed that the changes of MLR in the group with RP during radiotherapy were significantly different from those in the non-RP group (
conclusionMLR could predict radiation pneumonia in patients with thoracic tumor radiotherapy and achieve early monitoring, early prevention, and treatment.
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