Evidence map›Paper›PMID 33061454›Full record

ArticleOncoTargets and therapy2020

Response to Afatinib in a Patient with NSCLC Harboring Novel

Ling Lin, Xiaomai Wu, Shuangquan Yan, Yefei Zhu, Zhengqing Yan, Dongqing Lv, Hongfei Ge

Open access · goldAbstract readCase Reports
In one paragraph

Article in OncoTargets and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Advances in the management of non-small-cell lung cancer harbouringTherapeutic advances in medical oncology · 2023
    Review
  4. Review
  5. TargetingCancer discovery · 2021
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ling Lin *Department of Respiratory Medicine, Taizhou Hospital of Wenzhou Medical University, Taizhou, People's Republic of China.
Xiaomai Wu *Department of Respiratory Medicine, Taizhou Hospital of Wenzhou Medical University, Taizhou, People's Republic of China.ORCID 0000-0002-3115-3988
Shuangquan YanDepartment of Respiratory Medicine, Taizhou Hospital of Wenzhou Medical University, Taizhou, People's Republic of China.
Yefei ZhuDepartment of Respiratory Medicine, Taizhou Hospital of Wenzhou Medical University, Taizhou, People's Republic of China.
Zhengqing YanThe Medical Department, 3D Medicines Inc., Shanghai, People's Republic of China.
Dongqing LvDepartment of Respiratory Medicine, Taizhou Hospital of Wenzhou Medical University, Taizhou, People's Republic of China.
Hongfei GeDepartment of Thoracic Surgery, Taizhou Hospital of Wenzhou Medical University, Taizhou, People's Republic of China.
Wenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMost epidermal growth factor receptor (EGFR) exon 20 insertion (ex20ins) mutations are resistant to tyrosine kinase inhibitors (TKIs). While some non-small cell lung cancer (NSCLC) patients harboring special subtypes of CASE PRESENTATION: A 71-year-old non-smoker Chinese female was diagnosed with advanced lung adenocarcinoma harboring

conclusionThis is the first published case report of

Indexed as

afatinibEGFR exon 20 insertionslung adenocarcinomanext generation sequencing

Identifiers

PMID33061454
PMCPMC7533245
OpenAlexW3090826485

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.