Evidence map›Paper›PMID 33061386›Full record

ArticleNeuropsychiatric disease and treatment2020

Elevated Neutrophil-to-Lymphocyte Ratio Predicts Depression After Intracerebral Hemorrhage.

Xiuqun Gong, Zeyu Lu, Xiwu Feng, Chuanqing Yu, Min Xue, Liang Yu, Tao Wang, Xiaosi Cheng, Jun Lu, Mei Zhang

Open access · goldAbstract read
In one paragraph

Article in Neuropsychiatric disease and treatment, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
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  4. Review
  5. Article
  6. CNS-peripheral immune interactions in hemorrhagic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Xiuqun Gong *Department of Neurology, First Affiliated Hospital of Anhui University of Science and Technology, First People's Hospital of Huainan, Huainan 232001, Anhui, People's Republic of China.ORCID 0000-0002-3287-3135
Zeyu Lu *School of Medicine, Anhui University of Science and Technology, Huainan 232001, Anhui, People's Republic of China.
Xiwu Feng *Department of Cardiothoracic Surgery, First Affiliated Hospital of Anhui University of Science and Technology, First People's Hospital of Huainan, Huainan 232001, Anhui, People's Republic of China.
Chuanqing YuDepartment of Neurology, First Affiliated Hospital of Anhui University of Science and Technology, First People's Hospital of Huainan, Huainan 232001, Anhui, People's Republic of China.
Min XueDepartment of Neurology, First Affiliated Hospital of Anhui University of Science and Technology, First People's Hospital of Huainan, Huainan 232001, Anhui, People's Republic of China.
Liang YuDepartment of Neurology, First Affiliated Hospital of Anhui University of Science and Technology, First People's Hospital of Huainan, Huainan 232001, Anhui, People's Republic of China.
Tao WangDepartment of Neurology, First Affiliated Hospital of Anhui University of Science and Technology, First People's Hospital of Huainan, Huainan 232001, Anhui, People's Republic of China.
Xiaosi ChengDepartment of Neurology, First Affiliated Hospital of Anhui University of Science and Technology, First People's Hospital of Huainan, Huainan 232001, Anhui, People's Republic of China.
Jun LuDepartment of Medical Laboratory, School of Medicine, Anhui University of Science and Technology, Huainan 232001, Anhui, People's Republic of China.ORCID 0000-0003-4121-7815
Mei ZhangDepartment of Neurology, First Affiliated Hospital of Anhui University of Science and Technology, First People's Hospital of Huainan, Huainan 232001, Anhui, People's Republic of China.
Anhui University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeInflammation plays a critical role in the development of depression after intracerebral hemorrhage (ICH), while neutrophil-to-lymphocyte ratio (NLR) has been identified as a novel comprehensive inflammatory indicator in recent years. The aim of this study was to examine the association between NLR and depression after ICH. PATIENTS AND

methodsFrom January 2016 to December 2018, ICH patients were prospectively enrolled. NLR was measured at admission. Depression at 3 months after ICH was diagnosed according to the Hamilton Depression Scale (HAMD).

resultsOf the 372 enrolled patients, 107 (28.8%) were diagnosed with depression at 3 months after ICH. Patients with depression had a higher NLR (6.15 vs 3.55,

conclusionElevated NLR is associated with depression at 3 months after ICH, suggesting that NLR may be a significant biomarker to predict depression after ICH.

Indexed as

depressioninflammationintracerebral hemorrhageneutrophil-to-lymphocyte ratio

Identifiers

PMID33061386
PMCPMC7518785
OpenAlexW3087756587

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.