Evidence map›Paper›PMID 33061377›Full record

ArticleInternational journal of nanomedicine2020

Multifunctional Coating with Both Thermal Insulation and Antibacterial Properties Applied to Nickel-Titanium Alloy.

ZhiBo Liu, KangWen Xiao, ZhiQiang Hou, FeiFei Yan, Yan Chen, Lin Cai

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

ZhiBo Liu *Department of Orthopedics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, People's Republic of China.
KangWen Xiao *Department of Orthopedics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, People's Republic of China.
ZhiQiang HouDepartment of Orthopedics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, People's Republic of China.
FeiFei YanDepartment of Orthopedics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, People's Republic of China.
Yan ChenDepartment of Orthopedics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, People's Republic of China.
Lin CaiDepartment of Orthopedics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith excellent shape memory and superelastic properties, shape memory alloy (SMA) is an ideal actuator, and it can form smart structure for different applications in medical field. However, SMA devices cause apparent thermal damage to the surrounding tissues when it works in vivo, making the application of smart structure that is composed of SMA actuator in vivo is greatly limited.

methodsIn this paper, coating (APA) with PLA as the main body to limit the heat conduction, a multifunctional Ag nanoparticles (AgNPs)/polylactic acid (PLA)/Al2O3 was synthesized. The Al2O3 layer was formed by micro-arc oxidation (MAO) and AgNPs were synthesized by silver nitrate and ethylene glycol. Scanning electron microscopy, transmission electron microscope, and Fourier transform infrared spectra were applied to analyze the morphology and characterization of APA coating. The antimicrobial activity, thermal insulation activity, and biocompatibility of APA coating were furtherly explored and verified through animal experiments and immunohistochemistry.

resultsWith different particle sizes and concentrations of AgNPs, APA multi-functional films were successfully prepared. The Al2O3 layer was closely combined with SMA and formed a porous surface, so the PLA and AgNPs layers can firmly adhere to SMA, thus reducing the release of nickel ions in SMA. AgNPs gave APA coating excellent antibacterial activity and effectively inhibited the growth of Staphylococcus aureus. In addition, coupled with the low thermal conductivity of PLA and Al2O3, AgNPs were tightly anchored on the surface of PLA, which has high infrared reflectivity, making the APA coating obtain good thermal insulation performance.

conclusionWe have successfully prepared the APA coating and obtained the optimum amount of AgNPs, which makes it have good thermal insulation performance, good antibacterial activity and good biocompatibility, which provides a new prospect for the application of SMA.

Indexed as

TemperatureAluminum OxideAnimalsAnti-Bacterial AgentsCell LineCoated Materials, BiocompatibleMetal NanoparticlesMiceMicrobial Sensitivity TestsNickelPolyestersRabbitsSilverStaphylococcus aureusTitaniumAluminum OxideAnti-Bacterial AgentsCoated Materials, BiocompatibleNickelPolyesterspoly(lactide)SilverTitaniumtitanium nickelidemicro-arc oxidationnickel-titanium alloysilver nanoparticlesthermal insulation

Identifiers

PMID33061377
PMCPMC7532895

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.