ArticleInternational journal of nanomedicine2020
Magnesium-doped Nanostructured Titanium Surface Modulates Macrophage-mediated Inflammatory Response for Ameliorative Osseointegration.
Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The trial behind it
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Who cites it
25 citing papers in PubMed, 59 citations in OpenAlex.
- Beyond M1/M2: The Pivotal Role of Macrophage Metabolic Reprogramming in Chronic Bone Disease and Targeted Intervention.International journal of molecular sciences · 2026Review
- Surface modifications of titanium dental implants: optimizing antibacterial activity and osteoimmunomodulation.Frontiers in bioengineering and biotechnology · 2026Review
- Organic Acid-Based Anodization Process to Produce Bioactive Oxides on Titanium Implants.Materials (Basel, Switzerland) · 2025Article
- Engineering the Immune Response to Biomaterials.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Citrus-Fruit-Based Hydroxyapatite Anodization Coatings on Titanium Implants.Materials (Basel, Switzerland) · 2025Article
- A microenvironment responsive polyetheretherketone implant with antibacterial and osteoimmunomodulatory properties facilitates osseointegration.Bioactive materials · 2025Article
- Functionalized metal-organic framework and MOF-derived materials for bone regeneration applications.Frontiers in bioengineering and biotechnology · 2025Review
- Advanced surface modification techniques for titanium implants: a review of osteogenic and antibacterial strategies.Frontiers in bioengineering and biotechnology · 2025Review
- Machine Learning Approach to Investigating Macrophage Polarization on Various Titanium Surface Characteristics.BME frontiers · 2025Article
- The relationship between the secondary implant stability quotient and oxidized implant-related factors: A retrospective study.Heliyon · 2024Article
- Metal-organic frameworks in oral drug delivery.Asian journal of pharmaceutical sciences · 2024Article
- The regulatory effect of TiOBMC oral health · 2024Article
- Multifunctional nanomaterialsMaterials today. Bio · 2024Article
- Surface-modified titanium and titanium-based alloys for improved osteogenesis: A critical review.Heliyon · 2024Review
- Stability, biomechanics and biocompatibility analysis following different preparation strategies of hierarchical zeolite coatings on titanium alloy surfaces.Frontiers in bioengineering and biotechnology · 2023Article
- The 3D-Printed Ordered Bredigite Scaffold Promotes Pro-Healing of Critical-Sized Bone Defects by Regulating Macrophage Polarization.International journal of nanomedicine · 2023Article
- Immunomodulatory biomaterials for implant-associated infections: from conventional to advanced therapeutic strategies.Biomaterials research · 2022Review
- Immunomodulatory strategies for bone regeneration: A review from the perspective of disease types.Biomaterials · 2022Review
- Multi-omics analysis of oral bacterial biofilm on titanium oxide nanostructure modified implant surface:Materials today. Bio · 2022Article
- Hybridizing gellan/alginate and thixotropic magnesium phosphate-based hydrogel scaffolds for enhanced osteochondral repair.Materials today. Bio · 2022Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNext generation of coating materials on the surface of implants is designed with a paradigm shift from an inert material to an osteoimmunomodulatory material. Regulating immune response to biomedical implants through influencing the polarization of macrophage has been proven to be an effective strategy.
methodsThrough anodization and hydrothermal treatment, magnesium ion incorporated TiO
resultsMg ion release behavior results showed that MgN coating was successfully fabricated on the surface of titanium using anodization and hydrothermal technology. Scanning electron microscopy (SEM) images showed the morphology of the MgN coating on the titanium. The expression of inflammation-related genes
conclusionMgN coating on the titanium endowed the surface with immune-regulatory features and exerted an advantageous effect on osteogenesis, thereby providing excellent strategies for the surface modification of biomedical implants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.