Evidence map›Paper›PMID 33061370›Full record

ArticleInternational journal of nanomedicine2020

Extraction, Purification, and Characterization of Polysaccharides of

Antony V Samrot, Teeshalini Kudaiyappan, Ummu Bisyarah, Anita Mirarmandi, Etel Faradjeva, Amira Abubakar, Jenifer A Selvarani, Suresh Kumar Subbiah

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Effective separation of protein fromFrontiers in chemistry · 2023
    Article
  6. Article
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Antony V SamrotDepartment of Biomedical Sciences, Faculty of Medicine and Biomedical Sciences, MAHSA University, Jenjarom, Selangor 42610, Malaysia.ORCID 0000-0001-9536-0567
Teeshalini KudaiyappanDepartment of Biomedical Sciences, Faculty of Medicine and Biomedical Sciences, MAHSA University, Jenjarom, Selangor 42610, Malaysia.
Ummu BisyarahDepartment of Biomedical Sciences, Faculty of Medicine and Biomedical Sciences, MAHSA University, Jenjarom, Selangor 42610, Malaysia.
Anita MirarmandiDepartment of Biomedical Sciences, Faculty of Medicine and Biomedical Sciences, MAHSA University, Jenjarom, Selangor 42610, Malaysia.
Etel FaradjevaDepartment of Biomedical Sciences, Faculty of Medicine and Biomedical Sciences, MAHSA University, Jenjarom, Selangor 42610, Malaysia.
Amira AbubakarDepartment of Biomedical Sciences, Faculty of Medicine and Biomedical Sciences, MAHSA University, Jenjarom, Selangor 42610, Malaysia.
Jenifer A SelvaraniDepartment of Biotechnology, School of Bio and Chemical Engineering, Sathyabama Institute of Science and Technology, Sholinganallur, Chennai, Tamil Nadu 600119, India.ORCID 0000-0002-8885-6713
Suresh Kumar SubbiahDepartment of Medical Microbiology and Parasitology, Universiti Putra Malaysia, Serdang, Selangor 43400 UPM, Malaysia.
Mahsa University · MYSathyabama Institute of Science and Technology · INUniversiti Putra Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPlant gums consist of polysaccharides which can be used in the preparation of nanocarriers and provide a wide application in pharmaceutical applications including as drug delivery agents and the matrices for drug release. The objectives of the study were to collect plant gums from

methodsPlant gum was collected, polysaccharide was extracted, purified, characterized using UV-Vis, FTIR, TGA and GCMS and subjected to various bioactive studies. The purified polysaccharide was used for making curcumin-loaded nanocarriers using STMP (sodium trimetaphosphate). Bioactivities were performed on the crude, purified and drug-loaded nanocarriers. These polysaccharide-based nanocarriers were characterized using UV-Vis spectrophotometer, FTIR, SEM, and AFM. Drug release kinetics were performed for the drug-loaded nanocarriers.

resultsThe presence of glucose, xylose and sucrose was studied from the UV-Vis and GCMS analysis. Purified polysaccharides of both the plants showed antioxidant activity and also antibacterial activity against

conclusionThe extracted pure polysaccharide of

Indexed as

Anti-Bacterial AgentsAntioxidantsAraucariaBacillusCurcuminDrug CarriersDrug Delivery SystemsDrug LiberationGas Chromatography-Mass SpectrometryNanostructuresPlant GumsProsopisSpectroscopy, Fourier Transform InfraredThermogravimetryAnti-Bacterial AgentsAntioxidantsCurcuminDrug CarriersPlant GumsAraucaria heterophylla Lgum polysaccharideProsopis chilensis L

Identifiers

PMID33061370
PMCPMC7524200
OpenAlexW3088861428

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.