Evidence map›Paper›PMID 33061368›Full record

ReviewInternational journal of nanomedicine2020

The Applications of Carbon Nanotubes in the Diagnosis and Treatment of Lung Cancer: A Critical Review.

Mojgan Sheikhpour, Maryam Naghinejad, Alibakhsh Kasaeian, Armaghan Lohrasbi, Seyed Sadegh Shahraeini, Shahab Zomorodbakhsh

Open access · goldAbstract readReview
In one paragraph

Review in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Application of nanomedicines in tumor immunotherapy.Journal of molecular cell biology · 2025
    Review
  5. Review
  6. Treatment of lung diseasesMaterials today. Bio · 2025
    Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mojgan SheikhpourDepartment of Mycobacteriology and Pulmonary Research, Pasteur Institute of Iran, Tehran, Iran.ORCID 0000-0001-8802-7520
Maryam NaghinejadDepartment of Mycobacteriology and Pulmonary Research, Pasteur Institute of Iran, Tehran, Iran.ORCID 0000-0001-9926-7474
Alibakhsh KasaeianFaculty of New Sciences and Technologies, University of Tehran, Tehran, Iran.ORCID 0000-0002-4340-190X
Armaghan LohrasbiDepartment of Mycobacteriology and Pulmonary Research, Pasteur Institute of Iran, Tehran, Iran.
Seyed Sadegh ShahraeiniDepartment of Mycobacteriology and Pulmonary Research, Pasteur Institute of Iran, Tehran, Iran.ORCID 0000-0002-4854-570X
Shahab ZomorodbakhshDepartment of Chemistry, Mahshahr Branch, Islamic Azad University, Mahshahr, Iran.
Pasteur Institute of Iran · IRIslamic Azad University Mahshahr · IRUniversity of Tehran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The importance of timely diagnosis and the complete treatment of lung cancer for many people with this deadly disease daily increases due to its high mortality. Diagnosis and treatment with helping the nanoparticles are useful, although they have reasonable harms. This article points out that the side effects of using carbon nanotube (CNT) in this disease treatment process such as inflammation, fibrosis, and carcinogenesis are very problematic. Toxicity can reduce to some extent using the techniques such as functionalizing to proper dimensions as a longer length, more width, and greater curvature. The targeted CNT sensors can be connected to various modified vapors. In this regard, with helping this method, screening makes non-invasive diagnosis possible. Researchers have also found that nanoparticles such as CNTs could be used as carriers to direct drug delivery, especially with chemotherapy drugs. Most of these carriers were multi-wall carbon nanotubes (MWCNT) used for cancerous cell targeting. The results of laboratory and animal researches in the field of diagnosis and treatment became very desirable and hopeful. The collection of researches summarized has highlighted the requirement for a detailed assessment which includes CNT dose, duration, method of induction, etc., to achieve the most controlled conditions for animal and human studies. In the discussion section, 4 contradictory issues are discussed which are invited researchers to do more research to get clearer results.

Indexed as

Nanotubes, CarbonAnimalsAntineoplastic AgentsDrug CarriersDrug Delivery SystemsFibrosisHumansLung NeoplasmsToxicity TestsAntineoplastic AgentsDrug CarriersNanotubes, Carboncarbon nanotubesdrug deliverylung cancer detectionlung cancer treatmenttoxicity

Identifiers

PMID33061368
PMCPMC7522408
OpenAlexW3089272543

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.