Evidence map›Paper›PMID 33061364›Full record

ArticleInternational journal of nanomedicine2020

The Role of Silver Nanoparticles in a Treatment Approach for Multidrug-Resistant

Manar M Farouk, Amal El-Molla, Fayez A Salib, Yousef A Soliman, Mohamed Shaalan

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. Article
  3. Antibiotic Alternatives and Next-Generation Therapeutics forAntibiotics (Basel, Switzerland) · 2025
    Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Green Synthesis of Silver Nanoparticles fromMolecules (Basel, Switzerland) · 2025
    Article
  9. Article
  10. Iranian journal of veterinary research · 2025
    Article
  11. In vitro and in vivo efficacy of zinc oxide green nanoparticles against multidrug-resistant Salmonella Typhi.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Manar M FaroukDepartment of Internal Medicine and Infectious Diseases, Faculty of Veterinary Medicine, Cairo University, Giza 12211, Egypt.ORCID 0000-0002-0750-4151
Amal El-MollaDepartment of Internal Medicine and Infectious Diseases, Faculty of Veterinary Medicine, Cairo University, Giza 12211, Egypt.
Fayez A SalibDepartment of Internal Medicine and Infectious Diseases, Faculty of Veterinary Medicine, Cairo University, Giza 12211, Egypt.ORCID 0000-0003-1931-3958
Yousef A SolimanCentral Laboratory for Evaluation of Veterinary Biologics (CLEVB), Cairo, Egypt.ORCID 0000-0003-0141-8540
Mohamed ShaalanDepartment of Pathology, Faculty of Veterinary Medicine, Cairo University, Giza 12211, Egypt.ORCID 0000-0002-0741-3954
Cairo University · EGCentral Laboratory For Agricultural Expert Systems · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe main objective of this study is to investigate the antibacterial activity of silver nanoparticles (AgNPs) against multidrug-resistant

methodsThis study used chemical reduction synthesis of AgNPs to evaluate their antimicrobial effects by estimation of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) for each isolate using the microplate dilution method and tetrazolium salt reduction test to detect the viability percentage. In vivo treatment efficacy was assessed in mice by determining the viable count of

resultsAll recovered strains were identified as MDR with a prevalence of 4% and 3.6% in sheep and goats, respectively. The results of TEM, DLS, Zeta potential, and FTIR revealed typical characteristics of the synthesized AgNPs. Silver nanoparticles showed antibacterial activity against all recovered strains with MIC of ≤0.02-0.313 μg/mL (mean average 0.085±0.126 μg/mL) and MBC of 0.078-1.250 μg/mL (average 0.508±0.315 μg/mL). In vivo efficacy of AgNPs was observed by a reduction in the number of viable

conclusionThe study proved the effective ability of AgNPs to fight MDR

Indexed as

AnimalsAnti-Bacterial AgentsCitratesDrug Resistance, Multiple, BacterialDynamic Light ScatteringFecesGoatsMaleMetal NanoparticlesMiceMicrobial Sensitivity TestsSalmonellaSalmonella enteritidisSalmonella InfectionsSalmonella Infections, AnimalSheepAnti-Bacterial AgentsCitratesSilvertrisodium citratemiceminimum bactericidal concentrationminimum inhibitory concentrationmultidrug resistanceSalmonellasilver nanoparticles

Identifiers

PMID33061364
PMCPMC7520150
OpenAlexW3088403496

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.