Evidence map›Paper›PMID 33061301›Full record

ArticleDrug design, development and therapy2020

Anti-Tumor Xanthones from

Zhongyan Tang, Lihua Lu, Zhengxiang Xia

Open access · goldAbstract read
In one paragraph

Article in Drug design, development and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Zhongyan Tang *Department of Emergency and Critical Care Medicine, Jin Shan Hospital, Fudan University, Shanghai 201508, People's Republic of China.ORCID 0000-0002-9044-9180
Lihua Lu *Department of Neonatology, International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200030, People's Republic of China.
Zhengxiang XiaDepartment of Pharmacy, School & Hospital of Stomatology, Shanghai Engineering Research Center of Tooth Restoration and Regeneration, Tongji University, Shanghai 200072, People's Republic of China.
Jinshan Hospital of Fudan University · CNShanghai Jiao Tong University · CNTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOvarian cancer (OC) is a serious public health concern in the world. It is important to develop novel drugs to inhibit OC. PURPOSE: This study investigated the isolation, elucidation, efficiency, molecular docking, and pharmaceutical mechanisms of xanthones isolated from

methodsXanthones were isolated, and purified by different chromatography, including silica gel, reversed-phase silica gel (ODS-C

resultsBioassay-guided fractionation of the fruits of

conclusionIn conclusion, isojacareubin (

Indexed as

Antineoplastic Agents, PhytogenicApoptosisCell ProliferationDose-Response Relationship, DrugDrug Screening Assays, AntitumorEnzyme InhibitorsFemaleGarciniaHumansMAP Kinase Signaling SystemMolecular Docking SimulationMolecular StructureOvarian NeoplasmsPhosphatidylinositol 3-KinasesPoly(ADP-ribose) PolymerasesProto-Oncogene Proteins c-aktAntineoplastic Agents, PhytogenicEnzyme InhibitorsMTOR protein, humanPhosphatidylinositol 3-KinasesPoly(ADP-ribose) PolymerasesProto-Oncogene Proteins c-aktTOR Serine-Threonine KinasesXanthonesapoptosisGarcinia nujiangensismolecular dockingovarian cancer; OCxanthone

Identifiers

PMID33061301
PMCPMC7524179
OpenAlexW3088748288

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.