ReviewIndian journal of thoracic and cardiovascular surgery2020
DCD donations and outcomes of heart transplantation: the Australian experience.
Review in Indian journal of thoracic and cardiovascular surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Ex vivo heart perfusion: an updated systematic review.Heart failure reviews · 2024Pooled it
- Ex vivo heart perfusion induces time dependent inflammatory activation in human donor hearts.NPJ cardiovascular health · 2026Article
- Beating heart transplantation: A single center's initial experience and propensity-matched analysis against national registry data.JHLT open · 2026Article
- Primary graft dysfunction in donor after brain death vs normothermic regional perfusion heart transplants.JHLT open · 2026Article
- Sex differences in cardiac graft recovery and pathophysiologic changes in a rat model of donation after circulatory death.Scientific reports · 2025Article
- Article
- Days alive and out of the hospital at 1 year following heart transplant: Comparing donation after brain death versus after circulatory death.JHLT open · 2025Article
- Potential intermediate-term survival differences among heart transplant recipients from circulatory death vs brain death donors.JHLT open · 2025Article
- Donation After Circulatory Death following Withdrawal of Life-Sustaining Treatments. Are We Ready to Break the Dead Donor Rule?Journal of bioethical inquiry · 2025Article
- Early outcomes in heart transplantation using donation after circulatory death donors in patients bridged with durable left ventricular assist devices.The Journal of thoracic and cardiovascular surgery · 2025Article
- Cardiac donation after circulatory death in adult congenital heart disease: Early national experiences and outcomes.JTCVS open · 2025Article
- Brief hypothermic oxygenated perfusion provides cardioprotection in a pig model of donation after circulatory death.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025Article
- A critical evaluation of donor heart offer acceptance in the United Kingdom.Annals of cardiothoracic surgery · 2025Article
- Donation after circulatory death transplantation: a systematic review and meta-analysis of outcomes and methods of donation.Annals of cardiothoracic surgery · 2025Article
- Transplant international : official journal of the European Society for Organ Transplantation · 2025Review
- Expanding the Donor Pool.Methodist DeBakey cardiovascular journal · 2025Review
- Surgical techniques for cardiac allograft procurement and perfusion in controlled donation after circulatory death.Annals of cardiothoracic surgery · 2024Article
- Developing a thoracoabdominal normothermic regional perfusion (TA-NRP) program for the recovery of organs for thoracic transplant: lessons from the United States experience.Annals of cardiothoracic surgery · 2024Article
- Adult cardiac transplantation utilizing donors after circulatory death.Annals of cardiothoracic surgery · 2024Review
- The Dallas Donation after Circulatory Death Transplantation Summit: expanding donation after circulatory death procedures through process improvement, broader utilization, and innovation.Hepatobiliary surgery and nutrition · 2024Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThere is increasing clinical utilization of hearts from the donation after circulatory death (DCD) pathway with the aim of expanding the donor pool and mitigating the ever-present discrepancy between the inadequate availability of good quality donor hearts and the rising number of patients with end-stage heart failure.
methodsThis article reviews the rationale, practice, logistical factors, and 5-year experience of DCD heart transplantation at St Vincent's Hospital, Sydney.
findingsBetween July 2014 and July 2019, 69 DCD donor retrievals were undertaken resulting in 49 hearts being instrumented on an ex situ normothermic cardiac perfusion device. Seventeen (35%) of these hearts were declined and the remaining 32 (65%) were used for orthotopic DCD heart transplantation. At 5 years of follow-up, the 1-, 3-, and 5-year survival was 96%, 94%, and 94% for DCD hearts compared with 89%, 83%, and 82% respectively for donation after brain death (DBD) hearts (n.s). The immediate post-implant requirement for temporary extra-corporeal membrane oxygenation (ECMO) support for delayed graft function was 31% with no difference in rejection rates when compared with the contemporaneous cohort of patients transplanted with standard criteria DBD hearts. SUMMARY: DCD heart transplantation has become routine and incorporated into standard clinical practice by a handful of pioneering clinical transplant centres. The Australian experience demonstrates that excellent medium-term outcomes are achievable from the use of DCD hearts. These outcomes are consistent across the other centres and consequently favour a more rapid and wider uptake of heart transplantation using DCD donor hearts, which would otherwise be discarded.
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