Evidence map›Paper›PMID 33060844›Full record

ReviewNature reviews. Nephrology2020

COVID-19-associated acute kidney injury: consensus report of the 25th Acute Disease Quality Initiative (ADQI) Workgroup.

Mitra K Nadim, Lui G Forni, Ravindra L Mehta, Michael J Connor, Kathleen D Liu, Marlies Ostermann, Thomas Rimmelé, Alexander Zarbock, Samira Bell, Azra Bihorac and 25 more

Erratum issued 2 registry-linked trialsOpen access · hybridAbstract readConsensus StatementReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nature reviews. Nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 2 registered trials, which are not on this map. Cited by 387 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
387citing papers in PubMed, 3 pooled it
14.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04997915 completednot on this map

Acute Kidney Injury in COVID-19 Patients Admitted to the ICU: a Multicenter Cohort Analysis in 9 Large Hospitals in Belgium

TypeobservationalSponsorUniversity Hospital, GhentRan2020 to 2022Enrolled1,286ConditionsCritical Illness, COVID-19 Pneumonia, Acute Kidney InjuryArmsObservational study exploring the epidemiology and outcomes of AKI in critical COVID-19 patients admitted to the ICU
NCT05467956 completednot on this map

The Incidence of AKI in Critically-ill COVID -19 Patients, A Single Centre Retrospective Study From March 2020 Till September 2021.

TypeobservationalSponsorSultan Qaboos UniversityRan2020 to 2022Enrolled286ConditionsAcute Kidney Injury, COVID-19, Critically IllArmsCovid-19
3 · Its place in the literature

Who cites it

387 citing papers in PubMed, 3 syntheses or guidelines pooled it, 699 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Prognostic Performance of Cystatin C in COVID-19: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022
    Pooled it
  4. Trial
  5. Trial
  6. Electronic Phenotype for Detection, Staging, and Subtyping of Acute Kidney Injury.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2026
    Article
  7. Article
  8. Article
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  10. Kidney international reports · 2026
    Article
  11. Article
  12. Article
  13. Renal Biomarkers of Injury as Early Predictors of COVID-19 Associated Acute Kidney Injury: A Prospective Observational Trial (BRICOAKI Study).Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026
    Article
  14. Article
  15. Observational
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327 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

35 authors at 20 institutions in 13 countries.

Mitra K NadimDivision of Nephrology and Hypertension, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Lui G ForniDepartment of Clinical and Experimental Medicine, Faculty of Health Sciences, University of Surrey, Guildford, UK.ORCID http://orcid.org/0000-0002-0617-5309
Ravindra L MehtaDivision of Nephrology, Department of Medicine, University of California, San Diego, CA, USA.
Michael J ConnorDivisions of Pulmonary, Allergy, Critical Care, & Sleep Medicine, Division of Renal Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.ORCID http://orcid.org/0000-0001-7613-5583
Kathleen D LiuDivisions of Nephrology and Critical Care Medicine, Departments of Medicine and Anesthesia, University of California, San Francisco, CA, USA.ORCID http://orcid.org/0000-0003-4891-8649
Marlies OstermannDepartment of Intensive Care, Guy's & St Thomas' NHS Foundation Hospital, London, UK.
Thomas RimmeléDepartment of Anesthesiology and Intensive Care Medicine, Edouard Herriot Hospital, Hospices Civils de Lyon, Lyon, France.
Alexander ZarbockDepartment of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany.
Samira BellDivision of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, UK.ORCID http://orcid.org/0000-0001-9100-1575
Azra BihoracDepartment of Medicine, University of Florida, Gainesville, FL, USA.ORCID http://orcid.org/0000-0002-5745-2863
Vincenzo CantaluppiNephrology and Kidney Transplantation Unit, Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy.
Eric HosteIntensive Care Unit, Ghent University Hospital, Ghent University, Ghent, Belgium.ORCID http://orcid.org/0000-0001-9301-8055
Faeq Husain-SyedDivision of Nephrology, Pulmonology and Critical Care Medicine, Department of Medicine II, University Hospital Giessen and Marburg, Giessen, Germany.
Michael J GermainDivision of Nephrology, Renal Transplant Associates of New England, Baystate Medical Center U Mass Medical School, Springfield, MA, USA.ORCID http://orcid.org/0000-0001-7481-2421
Stuart L GoldsteinDivision of Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Shruti GuptaDivision of Renal Medicine, Brigham and Women's Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0002-5747-2151
Michael JoannidisDivision of Intensive Care and Emergency Medicine, Department of Medicine, Medical University of Innsbruck, Innsbruck, Austria.ORCID http://orcid.org/0000-0002-6996-0881
Kianoush KashaniDivision of Nephrology and Hypertension, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0003-2184-3683
Jay L KoynerDivision of Nephrology, Department of Medicine, University of Chicago, Chicago, IL, USA.
Matthieu LegrandDepartment of Anesthesiology and Perioperative Care, University of California San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0001-9788-5316
Nuttha LumlertgulDepartment of Intensive Care, Guy's & St Thomas' NHS Foundation Hospital, London, UK.ORCID http://orcid.org/0000-0003-1506-4253
Sumit MohanDepartment of Medicine, Division of Nephrology, Columbia University College of Physicians & Surgeons and New York Presbyterian Hospital, New York, NY, USA.
Neesh PannuDivision of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Zhiyong PengDivision of Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China.
Xose L Perez-FernandezServei de Medicina Intensiva, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain.ORCID http://orcid.org/0000-0002-5903-6927
Peter PickkersDepartment of Intensive Care Medicine, Radboudumc, Nijmegen, The Netherlands.
John ProwleCritical Care and Peri-operative Medicine Research Group, William Harvey Research Institute, Queen Mary University of London, London, UK.ORCID http://orcid.org/0000-0002-5002-2721
Thiago ReisDepartment of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, International Renal Research Institute of Vicenza, Vicenza, Italy.ORCID http://orcid.org/0000-0002-7071-117X
Nattachai SrisawatDivision of Nephrology, Excellence Center for Critical Care Nephrology, Critical Care Nephrology Research Unit, King Chulalongkorn Memorial Hospital, Chulalongkorn University, Bangkok, Thailand.
Ashita TolwaniDivision of Nephrology, Department of Medicine, University of Alabama, Birmingham, AL, USA.
Anitha VijayanDivision of Nephrology, Washington University School of Medicine, St. Louis, MO, USA.
Gianluca VillaSection of Anaesthesiology and Intensive Care, Department of Health Science, University of Florence, Florence, Italy.
Li YangRenal Division, Peking University First Hospital, Beijing, China.
Claudio RoncoDepartment of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, International Renal Research Institute of Vicenza, Vicenza, Italy.ORCID http://orcid.org/0000-0002-6697-4065
John A KellumDepartment of Critical Care Medicine, Center for Critical Care Nephrology, University of Pittsburgh, Pittsburgh, PA, USA. kellumja@upmc.edu.ORCID http://orcid.org/0000-0003-1995-2653
Chulalongkorn University · THUniversity of California, San Francisco · USBaystate Medical Center · USBellvitge University Hospital · ESBrigham and Women's Hospital · USCincinnati Children's Hospital Medical Center · USClinica De Doencas Renais De Brasilia · BREmory University · USGhent University Hospital · BEGuy's and St Thomas' NHS Foundation Trust · GBHospices Civils de Lyon · FRInnsbruck Medical University · ATMayo Clinic · USNewYork–Presbyterian Hospital · USPeking University · CNQueen Mary University of London · GBRadboud University Nijmegen · NLRoyal Surrey County Hospital · GBUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · ITUniversitätsklinikum Gießen und Marburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kidney involvement in patients with coronavirus disease 2019 (COVID-19) is common, and can range from the presence of proteinuria and haematuria to acute kidney injury (AKI) requiring renal replacement therapy (RRT; also known as kidney replacement therapy). COVID-19-associated AKI (COVID-19 AKI) is associated with high mortality and serves as an independent risk factor for all-cause in-hospital death in patients with COVID-19. The pathophysiology and mechanisms of AKI in patients with COVID-19 have not been fully elucidated and seem to be multifactorial, in keeping with the pathophysiology of AKI in other patients who are critically ill. Little is known about the prevention and management of COVID-19 AKI. The emergence of regional 'surges' in COVID-19 cases can limit hospital resources, including dialysis availability and supplies; thus, careful daily assessment of available resources is needed. In this Consensus Statement, the Acute Disease Quality Initiative provides recommendations for the diagnosis, prevention and management of COVID-19 AKI based on current literature. We also make recommendations for areas of future research, which are aimed at improving understanding of the underlying processes and improving outcomes for patients with COVID-19 AKI.

Indexed as

Acute Kidney InjuryAnticoagulantsConsensusCOVID-19HumansRenal Replacement TherapyRisk FactorsSARS-CoV-2Anticoagulants

Identifiers

PMID33060844
PMCPMC7561246
OpenAlexW3092778876

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.