Evidence map›Paper›PMID 33060833›Full record

ArticleHypertension research : official journal of the Japanese Society of Hypertension2021

Development and validation of a nomogram for the early prediction of preeclampsia in pregnant Chinese women.

Chao-Yan Yue, Jiang-Ping Gao, Chun-Yi Zhang, Ying-Hua Ni, Chun-Mei Ying

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In one paragraph

Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
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  9. Preeclampsia up to date-What's going on?Hypertension research : official journal of the Japanese Society of Hypertension · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Chao-Yan YueDepartment of Laboratory Medicine, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
Jiang-Ping GaoCollege of Engineering and Computer Science, Australian National University, Canberra, ACT, Australia.
Chun-Yi ZhangDepartment of Laboratory Medicine, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
Ying-Hua NiDepartment of Laboratory Medicine, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
Chun-Mei YingDepartment of Laboratory Medicine, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China. ycmzh2012@163.com.
Obstetrics and Gynecology Hospital of Fudan University · CNAustralian National University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To make early predictions of preeclampsia before diagnosis, we developed and validated a new nomogram for the early prediction of preeclampsia in pregnant Chinese women. A stepwise regression model was used for feature selection. Multivariable logistic regression analysis was used to develop the prediction model. We incorporated BMI, blood pressure, uterine artery ultrasound parameters, and serological indicator risk factors, and this was presented with a nomogram. The performance of the nomogram was assessed with respect to its calibration, discrimination, and clinical usefulness. Internal validation was assessed. The signature, which consisted of 11 selected features, was associated with preeclampsia status (P < 0.1) for the development dataset. Predictors contained in the individualized prediction nomogram included BMI, blood pressure, uterine artery ultrasound parameters, and serological indicator levels. The model showed good discrimination, with an area under the ROC curve of 0.8563 (95% CI: 0.8364-0.8761) and good calibration. The nomogram still had good discrimination and good calibration when applied to the validation dataset (area under ROC curve of 0.8324, 95% CI: 0.7873-0.8775). Decision curve analysis demonstrated that the nomogram was clinically useful. The nomogram presented in this study incorporates BMI, blood pressure, uterine artery ultrasound parameters, and serological indicators and can be conveniently used to facilitate the individualized prediction of preeclampsia.

Indexed as

NomogramsPre-EclampsiaChinaFemaleHumansPredictive Value of TestsPregnancyReproducibility of ResultsInhibin-ANomogramPredictionPreeclampsiaUterine artery Doppler

Identifiers

PMID33060833
OpenAlexW3093057820

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.