Evidence map›Paper›PMID 33060814›Full record

ArticleThe Journal of antibiotics2021

Characterization of compound A, a novel lincomycin derivative active against methicillin-resistant Staphylococcus aureus.

Yoko Hirai, Kazunori Maebashi, Keiko Yamada, Yoshinari Wakiyama, Ko Kumura, Eijiro Umemura, Keiichi Ajito

Abstract read
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In one paragraph

Article in The Journal of antibiotics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Yoko HiraiPharmacology Research Laboratory, Pharmaceutical Research Center, Meiji Seika Pharma Co., Ltd., Yokohama, Japan. youko.inoue.aa@meiji.com.
Kazunori MaebashiPharmacology Research Laboratory, Pharmaceutical Research Center, Meiji Seika Pharma Co., Ltd., Yokohama, Japan.
Keiko YamadaPharmacology Research Laboratory, Pharmaceutical Research Center, Meiji Seika Pharma Co., Ltd., Yokohama, Japan.
Yoshinari WakiyamaMedical Chemistry Laboratory, Pharmaceutical Research Center, Meiji Seika Pharma Co., Ltd., Yokohama, Japan.
Ko KumuraMedical Chemistry Laboratory, Pharmaceutical Research Center, Meiji Seika Pharma Co., Ltd., Yokohama, Japan.
Eijiro UmemuraMedical Chemistry Laboratory, Pharmaceutical Research Center, Meiji Seika Pharma Co., Ltd., Yokohama, Japan.
Keiichi AjitoMedical Chemistry Laboratory, Pharmaceutical Research Center, Meiji Seika Pharma Co., Ltd., Yokohama, Japan.
Kitasato University · JPMeiji University · JPMicrobial Chemistry Research Foundation · JPUnitika (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is one of causative bacteria for hospital- and community-acquired infections. In order to overcome MRSA infection, we synthesized compound A, a lincomycin derivative, and evaluated the biological properties. The MIC

Indexed as

AbscessAnimalsAnti-Bacterial AgentsBinding SitesClindamycinDrug Resistance, BacterialFemaleLincomycinLinezolidMaleMethicillin-Resistant Staphylococcus aureusMiceMice, Inbred ICRMicrobial Sensitivity TestsMitochondria, LiverRNA, Ribosomal, 23SAnti-Bacterial AgentsClindamycinLincomycinLinezolidRNA, Ribosomal, 23S

Identifiers

PMID33060814
OpenAlexW3092766063

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.