ArticleScientific reports2020
Experimental optimization of the energy for breast-CT with synchrotron radiation.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Radiomic Characterization of Breast Tissue from Breast CT Images Obtained with Synchrotron Beams.Tomography (Ann Arbor, Mich.) · 2026Article
- Signal-to-noise and spatial resolution in in-line imaging. 3. Optimization using a simple model.Journal of synchrotron radiation · 2026Article
- High-energy X-ray phase-contrast CT of an adult human chest phantom.Scientific reports · 2025Article
- Low-dose, high-resolution CT of infant-sized lungs via propagation-based phase contrast.Scientific reports · 2025Article
- Comparison of three reconstruction algorithms for low-dose phase-contrast computed tomography of the breast with synchrotron radiation.Medical physics · 2025Article
- Application of Synchrotron Radiation in Fundamental Research and Clinical Medicine.Biomedicines · 2025Review
- Low-density tissue scaffold imaging by synchrotron radiation propagation-based imaging computed tomography with helical acquisition mode.Journal of synchrotron radiation · 2023Article
- Anatomical study of the red flour beetle using synchrotron radiation X-ray phase-contrast micro-tomography.Journal of anatomy · 2023Review
- Exploring Compound Eyes in Adults of Four Coleopteran Species Using Synchrotron X-ray Phase-Contrast Microtomography (SR-PhC Micro-CT).Life (Basel, Switzerland) · 2022Article
- Motion artifacts assessment and correction using optical tracking in synchrotron radiation breast CT.Medical physics · 2021Article
- Effect of x-ray energy on the radiological image quality in propagation-based phase-contrast computed tomography of the breast.Journal of medical imaging (Bellingham, Wash.) · 2021Article
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Breast Computed Tomography (bCT) is a three-dimensional imaging technique that is raising interest among radiologists as a viable alternative to mammographic planar imaging. In X-rays imaging it would be desirable to maximize the capability of discriminating different tissues, described by the Contrast to Noise Ratio (CNR), while minimizing the dose (i.e. the radiological risk). Both dose and CNR are functions of the X-ray energy. This work aims at experimentally investigating the optimal energy that, at fixed dose, maximizes the CNR between glandular and adipose tissues. Acquisitions of both tissue-equivalent phantoms and actual breast specimens have been performed with the bCT system implemented within the Syrma-3D collaboration at the Syrmep beamline of the Elettra synchrotron (Trieste). The experimental data have been also compared with analytical simulations and the results are in agreement. The CNR is maximized at energies around 26-28 keV. These results are in line with the outcomes of a previously presented simulation study which determined an optimal energy of 28 keV for a large set of breast phantoms with different diameters and glandular fractions. Finally, a study on photon starvation has been carried out to investigate how far the dose can be reduced still having suitable images for diagnostics.
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