ArticleScientific reports2020
The immune response of bats differs between pre-migration and migration seasons.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 44 citations in OpenAlex.
- Total Immunoglobulin G Variation Through the Phenological Cycle of Migrant and Resident Lesser Long-Nosed Bats (Leptonycteris yerbabuenae) in the Drylands of Mexico and Its Relationship With Bacterial Killing-Ability of Plasma.Journal of experimental zoology. Part A, Ecological and integrative physiology · 2026Article
- Adapting flow cytometry for studying immune cell seasonality in wild migratory bats.bioRxiv : the preprint server for biology · 2026Article
- Contrasting phagocyte respiratory burst responses in two European bat species during hibernation.Frontiers in immunology · 2026Article
- To Migrate or not to Migrate? Exploring the Genomic Basis of Partial Migratory Behavior in Bats.Genome biology and evolution · 2025Article
- Diverse hosts, diverse immune systems: Evolutionary variation in bat immunology.Annals of the New York Academy of Sciences · 2025Review
- Multiple factors contribute to female dominance in migratory bioflows.Open biology · 2025Article
- Studying bats using a One Health lens: bridging the gap between bat virology and disease ecology.Journal of virology · 2024Review
- Controlled expression of avian pre-migratory fattening influences indices of innate immunity.Biology open · 2024Article
- Article
- Bat behavioral immune responses in social contexts: current knowledge and future directions.Frontiers in immunology · 2023Review
- Establishment of a Captive Cave Nectar Bat (Journal of the American Association for Laboratory Animal Science : JAALAS · 2022Article
- Induced bacterial sickness causes inflammation but not blood oxidative stress in Egyptian fruit bats (Conservation physiology · 2022Article
- Baseline of Physiological Body Temperature and Hematological Parameters in CaptiveFrontiers in physiology · 2022Article
- A meta-analysis of impacts of immune response and infection on oxidative status in vertebrates.Conservation physiology · 2022Article
- Sick bats stay home alone: fruit bats practice social distancing when faced with an immunological challenge.Annals of the New York Academy of Sciences · 2021Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Maintaining a competent immune system is energetically costly and thus immunity may be traded against other costly traits such as seasonal migration. Here, we tested in long-distance migratory Nathusius' pipistrelles (Pipistrellus nathusii), if selected branches of immunity are expressed differently in response to the energy demands and oxidative stress of aerial migration. During the migration period, we observed higher baseline lymphocyte and lower neutrophil levels than during the pre-migration period, but no stronger response of cellular effectors to an antigen challenge. Baseline plasma haptoglobin, as a component of the humoral innate immunity, remained similar during both seasons, yet baseline plasma haptoglobin levels increased by a factor of 7.8 in migratory bats during an immune challenge, whereas they did not change during the pre-migration period. Oxidative stress was higher during migration than during pre-migration, yet there was no association between blood oxidative status and immune parameters, and immune challenge did not trigger any changes in oxidative stress, irrespective of season. Our findings suggest that humoral effectors of the acute phase response may play a stronger role in the first-line defense against infections for migrating bats compared to non-migrating bats. We conclude that Nathusius' pipistrelles allocate resources differently into the branches of their immune system, most likely following current demands resulting from tight energy budgets during migration.
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