Evidence map›Paper›PMID 33060705›Full record

ArticleScientific reports2020

Association of cancer screening and residing in a coal-polluted East Asian region with overall survival of lung cancer patients: a retrospective cohort study.

Runxiang Yang, Ming He, Dongmei Wang, Rongrong Ye, Lu Li, Rouyu Deng, Mohsin Shah, Sai-Ching Jim Yeung

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Runxiang YangThe Second Department of Medical Oncology, Yunnan Cancer Hospital, Kunming, Yunnan, The People's Republic of China. 13888876721@163.com.
Ming HeThe Second Department of Medical Oncology, Yunnan Cancer Hospital, Kunming, Yunnan, The People's Republic of China.
Dongmei WangThe Second Department of Medical Oncology, Yunnan Cancer Hospital, Kunming, Yunnan, The People's Republic of China.
Rongrong YeThe Second Department of Medical Oncology, Yunnan Cancer Hospital, Kunming, Yunnan, The People's Republic of China.
Lu LiDepartment of Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, The People's Republic of China.
Rouyu DengThe Second Department of Medical Oncology, Yunnan Cancer Hospital, Kunming, Yunnan, The People's Republic of China.
Mohsin ShahCenter for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Sai-Ching Jim YeungDepartment of Emergency Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Second People's Hospital of Yunnan Province · CNSun Yat-sen University · CNThe University of Texas MD Anderson Cancer Center · USUniversity of Pennsylvania · US

Funding

Clinical Pharmacoepidemiology Training ProgramT32GM075766 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Sean Hennessy, Charles Edward Leonard · 2006 to 2026
$8.4M
NIGMS NIH HHS T32 GM075766
6 · The paper itself

Abstract

Lung cancer is the leading cause of cancer death worldwide. The Xuanwei-Fuyuan (XF) region of Yunnan, China has a high incidence of lung cancer from coal-related pollution. Effort to raise public awareness screening for lung cancer has been ongoing. We retrospectively analyzed overall survival (OS) of lung cancer patients of a tertiary cancer center in Yunnan to investigate screening and regional residential status as predictive factors. Consecutive cases of newly diagnosed lung cancer were reviewed. The lung cancer cases diagnosed by screening were more likely to be early-staged and treated by surgery than those diagnosed not by screening. In patients diagnosed not by screening, XF residential status was a significant predictor of improved OS. Frailty model detected significant heterogeneity associated with region of residence in unscreened patients. Potential biases associated with screening were examined by Monte Carlo simulations and sensitivity analyses. Focused effort in cancer screening and increased public awareness of pollution-related lung cancer in XF might have led to early diagnosis and improved OS, and increased investment in health care resources in high risk areas may have produced additional unobserved factors that underlay the association of XF residential status with improved OS in patients diagnosed not by screening.

Indexed as

AgedChinaCoalEarly Detection of CancerEnvironmental PollutantsFemaleHumansIncidenceLung NeoplasmsMaleMiddle AgedRetrospective StudiesSurvival RateCoalEnvironmental Pollutants

Identifiers

PMID33060705
PMCPMC7566617
OpenAlexW3093305217

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.