Evidence map›Paper›PMID 33060676›Full record

ArticleScientific reports2020

Clinical characteristics of "re-positive" discharged COVID-19 pneumonia patients in Wuhan, China.

Shengyang He, Kefu Zhou, Mengyun Hu, Chun Liu, Lihua Xie, Shenghua Sun, Wenwu Sun, Liangkai Chen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  4. What might COVID-19 patients experience after recovery? A comprehensive review.The International journal of pharmacy practice · 2022
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  10. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Shengyang HeRespiratory and Critical Care Medicine Department, The Third Xiangya Hospital of Central South University, Changsha, China.
Kefu ZhouRespiratory and Critical Care Medicine Department, The Third Xiangya Hospital of Central South University, Changsha, China.
Mengyun HuRespiratory and Critical Care Medicine Department, The Third Xiangya Hospital of Central South University, Changsha, China.
Chun LiuRespiratory and Critical Care Medicine Department, The Third Xiangya Hospital of Central South University, Changsha, China.
Lihua XieRespiratory and Critical Care Medicine Department, The Third Xiangya Hospital of Central South University, Changsha, China.
Shenghua SunRespiratory and Critical Care Medicine Department, The Third Xiangya Hospital of Central South University, Changsha, China.
Wenwu SunIntensive Care Unit, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. sunwenwuzxyy@163.com.
Liangkai ChenDepartment of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. clk@hust.edu.cn.
Central South University · CNThird Xiangya Hospital · CNHuazhong University of Science and Technology · CN

Funding

China Scholarship Council 201806370194National Natural Science Foundation of China 81770042
6 · The paper itself

Abstract

To analyze the clinical characteristics of re-positive discharged COVID-19 patients and find distinguishing markers. The demographic features, clinical symptoms, laboratory results, comorbidities, co-infections, treatments, illness severities and chest CT scan results of 267 patients were collected from 1st January to 15th February 2020. COVID-19 was diagnosed by RT-PCR. Clinical symptoms and nucleic acid test results were collected during the 14 days post-hospitalization quarantine. 30 out of 267 COVID-19 patients were detected re-positive during the post-hospitalization quarantine. Re-positive patients could not be distinguished by demographic features, clinical symptoms, laboratory results, comorbidities, co-infections, treatments, chest CT scan results or subsequent clinical symptoms. However, re-positive rate was found to be correlated to illness severity, according the Acute Physiology and Chronic Health Evaluation II (APACHE II) severity-of-disease classification system, and the confusion, urea, respiratory rate and blood pressure (CURB-65) score. Common clinical characteristics were not able to distinguish re-positive patients. However, severe and critical cases classified high according APACHE II and CURB-65 scores, were more likely to become re-positive after discharge.

Indexed as

AdultAgedBetacoronavirusChinaComorbidityCoronavirus InfectionsCOVID-19FemaleFollow-Up StudiesHumansLogistic ModelsMaleMiddle AgedPandemicsPatient DischargePneumonia, ViralRNA, Viral

Identifiers

PMID33060676
PMCPMC7562721
OpenAlexW3092698892

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.