Evidence map›Paper›PMID 33060659›Full record

Observational studyScientific reports2020

Quantitative bone single photon emission computed tomography analysis of the effects of duration of bisphosphonate administration on the parietal bone.

Hironobu Hata, Tomoka Kitao, Jun Sato, Takuya Asaka, Kenji Imamachi, Masaaki Miyakoshi, Kenji Hirata, Keiichi Magota, Yamato Munakata, Tohru Shiga and 2 more

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. SPECT/CT imaging: quantifyingAnnals of nuclear medicine · 2024
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hironobu HataDepartment of Dentistry and Oral Surgery, Hokkaido Cancer Center, 3-54, Kikusui4-Jyo 2-Tyoume, Shiroishi-Ku, Sapporo, Japan. hata.hironobu.wq@mail.hosp.go.jp.ORCID 0000-0002-0077-7026
Tomoka KitaoDepartment of Radiology, Hokkaido Medical Center, 1-1, Yamanote5-Jyo 7-Tyoume, Nishi-ku, Sapporo, Japan.
Jun SatoOral Diagnosis and Medicine, Department of Oral Pathobiological Science, Faculty of Dental Medicine, Hokkaido University, Nishi 7-Tyoume Kita13-Jyo, Kita-Ku, Sapporo, Japan.
Takuya AsakaOral Diagnosis and Medicine, Department of Oral Pathobiological Science, Faculty of Dental Medicine, Hokkaido University, Nishi 7-Tyoume Kita13-Jyo, Kita-Ku, Sapporo, Japan.
Kenji ImamachiDepartment of Dentistry and Oral Surgery, Hokkaido Cancer Center, 3-54, Kikusui4-Jyo 2-Tyoume, Shiroishi-Ku, Sapporo, Japan.
Masaaki MiyakoshiDepartment of Maxillofacial Radiology, Graduate School of Medical and Dental Sciences, Kagoshima University, 1-35-8, Sakuragaoka, Kagoshima, Japan.
Kenji HirataDepartment of Diagnostic Imaging, Graduate School of Medicine, Hokkaido University, Nishi 7-Tyoume Kita15-Jyo, Kita-Ku, Sapporo, Japan.
Keiichi MagotaDepartment of Diagnostic Imaging, Graduate School of Medicine, Hokkaido University, Nishi 7-Tyoume Kita15-Jyo, Kita-Ku, Sapporo, Japan.
Yamato MunakataDepartment of Diagnostic Imaging, Graduate School of Medicine, Hokkaido University, Nishi 7-Tyoume Kita15-Jyo, Kita-Ku, Sapporo, Japan.
Tohru ShigaAdvanced Clinical Research Center, Fukushima Global Medical Science Center, Fukushima Medical University, 1, Hikarigaoka, Fukushima, Japan.
Yutaka YamazakiGerodontology, Department of Oral Health Science, Faculty of Dental Medicine, Hokkaido University, Nishi 7-Tyoume Kita13-Jyo, Kita-Ku, Sapporo, Japan.
Yoshimasa KitagawaOral Diagnosis and Medicine, Department of Oral Pathobiological Science, Faculty of Dental Medicine, Hokkaido University, Nishi 7-Tyoume Kita13-Jyo, Kita-Ku, Sapporo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Effects of long-term bisphosphonate (BP) administration on the metabolism of healthy bone and the concomitant changes in imaging are unclear. Hence, we aimed to retrospectively investigate the effects of long-term BP administration on the intact parietal bone using the standardised uptake value (SUV) derived from single photon emission computed tomography (SPECT). We enrolled 29 patients who had odontogenic infection, osteoporosis, bone metastasis cancer, or rheumatoid arthritis, and classified them into BP-naïve: A (14 patients) and BP-treated: B, < 4 years (7 patients) and C, ≥ 4 years (8 patients) groups. We measured the maximum bilateral SUV (SUVmax) of the parietal bone using quantitative bone SPECT software. There were significant differences in the duration of BP administration and SUVmax of the parietal bone among the diseases (P < 0.0001 and P = 0.0086, respectively). There was a positive correlation between the duration of BP administration and SUVmax of the parietal bone (r

Indexed as

AgedAged, 80 and overArthritis, RheumatoidBlood PressureBone NeoplasmsCross-Sectional StudiesDiphosphonatesFemaleHumansInfectionsMaleMiddle AgedNeoplasm MetastasisOdontoid ProcessOsteoporosisParietal BoneDiphosphonatesTechnetium

Identifiers

PMID33060659
PMCPMC7567830

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.