ArticleLearning & memory (Cold Spring Harbor, N.Y.)2020
Using rat operant delayed match-to-sample task to identify neural substrates recruited with increased working memory load.
Article in Learning & memory (Cold Spring Harbor, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- Prefrontal parvalbumin neurons mediate working memory in a task demand-dependent manner.Nature communications · 2026Article
- Contextual inference through flexible integration of environmental features and behavioural outcomes.PLoS computational biology · 2026Article
- Post-methamphetamine working memory decline predicts relapse vulnerability in rats and is rescued by mGlu3 receptor activation.Psychopharmacology · 2026Article
- Developmental Pb exposure increases rate of forgetting on a delayed matching-to-sample task among Mexican children.Science advances · 2025Article
- Regulation of working memory switches from striatal dopamine D2-receptor to D1-receptor neurons under high cognitive load.PLoS biology · 2025Article
- Reduction of APOE accounts for neurobehavioral deficits in fetal alcohol spectrum disorders.Molecular psychiatry · 2024Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The delayed match-to-sample task (DMS) is used to probe working memory (WM) across species. While the involvement of the PFC in this task has been established, limited information exists regarding the recruitment of broader circuitry, especially under the low- versus high-WM load. We sought to address this question by using a variable-delay operant DMS task. Male Sprague-Dawley rats were trained and tested to determine their baseline WM performance across all (0- to 24-sec) delays. Next, rats were tested in a single DMS test with either 0- or 24-sec fixed delay, to assess low-/high-load WM performance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.