ArticleJournal of epidemiology and community health2021
Excess mortality in England and Wales during the first wave of the COVID-19 pandemic.
Article in Journal of epidemiology and community health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 2 of them syntheses that pooled it.
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Who cites it
67 citing papers in PubMed, 2 syntheses or guidelines pooled it, 118 citations in OpenAlex.
- Excess all-cause deaths stratified by sex and age in Peru: a time series analysis during the COVID-19 pandemic.BMJ open · 2022Pooled it
- The Impact of Age Difference on the Efficacy and Safety of COVID-19 Vaccines: A Systematic Review and Meta-Analysis.Frontiers in immunology · 2021Pooled it
- Non-COVID-19 mortality among older people or with chronic conditions during year 2020 in France: a nationwide cohort study.BMC public health · 2025Article
- Excess mortality in older adults and cumulative excess mortality across all ages during the COVID-19 pandemic in the 20 countries with the highest mortality rates worldwide.Osong public health and research perspectives · 2025Article
- All-Cause and Cause-Specific Excess Mortality During the First Two Years of the COVID-19 Pandemic in North-East of Iran: Reiterating the Significance of High-Quality Healthcare Systems.International journal of health policy and management · 2025Article
- Non-communicable diseases: research priorities to mitigate impact of health system shocks.BMJ (Clinical research ed.) · 2024Article
- Gender-Based Socio-Economic Inequalities in the Pre-Vaccination Era of the COVID-19 Pandemic in Istanbul: A Neighborhood-Level Analysis of Excess Mortality.Healthcare (Basel, Switzerland) · 2024Article
- Has the first year of the COVID pandemic impacted the trends in obesity-related CVD mortality between 1999 and 2019 in the United States?International journal of cardiology. Cardiovascular risk and prevention · 2024Article
- Spatial Variation in Excess Mortality Across Europe: A Cross-Sectional Study of 561 Regions in 21 Countries.Journal of epidemiology and global health · 2024Article
- Spatial disparities in the mortality burden of the covid-19 pandemic across 569 European regions (2020-2021).Nature communications · 2024Article
- A comparison of excess deaths by UK country and region during the first year of the COVID-19 pandemic.European journal of public health · 2024Article
- Regional variation of COVID-19 admissions, acute kidney injury and mortality in England - a national observational study using administrative data.BMC infectious diseases · 2024Observational
- Deprivation effects on length of stay and death of hospitalised COVID-19 patients in Greater Manchester.International journal of population data science · 2024Article
- Estimating subnational excess mortality in times of pandemic. An application to French départements in 2020.PloS one · 2024Article
- Article
- Age and sex differences in cause-specific excess mortality and years of life lost associated with COVID-19 infection in the Swedish population.European journal of public health · 2023Observational
- Cardiovascular Health Care Implications of the COVID-19 pandemic.Heart failure clinics · 2023Review
- Article
- Cerebro-/Cardiovascular Collateral Damage During the COVID-19 Pandemic: Fact or Fiction?Journal of clinical neurology (Seoul, Korea) · 2023Review
- A predictive model for disease severity among COVID-19 elderly patients based on IgG subtypes and machine learning.Frontiers in immunology · 2023Article
7 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDeaths during the COVID-19 pandemic result directly from infection and exacerbation of other diseases and indirectly from deferment of care for other conditions, and are socially and geographically patterned. We quantified excess mortality in regions of England and Wales during the pandemic, for all causes and for non-COVID-19-associated deaths.
methodsWeekly mortality data for 1 January 2010 to 1 May 2020 for England and Wales were obtained from the Office of National Statistics. Mean-dispersion negative binomial regressions were used to model death counts based on pre-pandemic trends and exponentiated linear predictions were subtracted from: (i) all-cause deaths and (ii) all-cause deaths minus COVID-19 related deaths for the pandemic period (week starting 7 March, to week ending 8 May).
findingsBetween 7 March and 8 May 2020, there were 47 243 (95% CI: 46 671 to 47 815) excess deaths in England and Wales, of which 9948 (95% CI: 9376 to 10 520) were not associated with COVID-19. Overall excess mortality rates varied from 49 per 100 000 (95% CI: 49 to 50) in the South West to 102 per 100 000 (95% CI: 102 to 103) in London. Non-COVID-19 associated excess mortality rates ranged from -1 per 100 000 (95% CI: -1 to 0) in Wales (ie, mortality rates were no higher than expected) to 26 per 100 000 (95% CI: 25 to 26) in the West Midlands.
interpretationThe COVID-19 pandemic has had markedly different impacts on the regions of England and Wales, both for deaths directly attributable to COVID-19 infection and for deaths resulting from the national public health response.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.