ReviewJournal of the American College of Cardiology2020
Challenges in Cardiac and Pulmonary Sarcoidosis: JACC State-of-the-Art Review.
Review in Journal of the American College of Cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
118 citing papers in PubMed, 1 synthesis or guideline pooled it, 198 citations in OpenAlex.
- The prognostic role of cardiac positron emission tomography imaging in patients with sarcoidosis: A systematic review.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Pooled it
- Seeing Beyond the Surface: ECG Clues of Multilayer Arrhythmogenic Substrate.JACC. Case reports · 2026Article
- Surgical Cardiac Sympathetic Denervation in Active Inflammatory Cardiac Sarcoidosis: Rethinking Conventional Timing Paradigms.JACC. Case reports · 2026Article
- Overlap syndrome between sarcoidosis and Sjögren's disease presenting as hypopituitarism: case report and review of literature.Endocrine journal · 2026Review
- Position Statement on Multimodal Cardiac Imaging in Patients with Systemic Diseases - 2026.Arquivos brasileiros de cardiologia · 2026Article
- Reversible Chronotropic Incompetence in Early Cardiac Sarcoidosis Assessed by Serial Exercise Echocardiography.JACC. Case reports · 2026Article
- Neurological involvement and pregnancy outcomes in autoimmune disease: mechanisms, clinical implications, and research gaps.Rheumatology international · 2026Review
- Diagnostic challenges in isolated cardiac sarcoidosis.ESC heart failure · 2026Review
- Case report on investigational modular cardiac rhythm management system: wireless communication between leadless pacemaker and subcutaneous defibrillator in cardiac sarcoidosis with limited vascular access.European heart journal. Case reports · 2026Article
- Redefining Cardiac Sarcoidosis with Advanced Imaging and Therapeutic Strategies.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2026Review
- Comprehensive Assessment of Biventricular and Biatrial Mechanics in Patients with Extracardiac Sarcoidosis Without Fibrotic Pulmonary Involvement.Journal of clinical medicine · 2026Article
- Cardiovascular Manifestations and Immunobiology of Sarcoidosis.Arteriosclerosis, thrombosis, and vascular biology · 2026Review
- Cardiac Sarcoidosis: Pathophysiology and Diagnostic-Therapeutic Processes.Reviews in cardiovascular medicine · 2026Review
- Cardiac sarcoidosis with a twist - active and fibrotic sarcoid with antiphospholipid positivity: A case report.World journal of cardiology · 2025Article
- [Bloqueo auriculoventricular completo como manifestación clínica de sarcoidosis cardiaca].Archivos de cardiologia de Mexico · 2025Article
- Increased Mortality and Morbidity in Patients With Heart Failure With Sarcoidosis Compared With Other Causes: A Propensity-Matched Nationwide Cohort Study.Journal of the American Heart Association · 2025Article
- Clinical and Demographic Characteristics of Oral Sarcoidosis: A Systematic Review of Case Reports and Case Series.Journal of clinical medicine · 2025Review
- Cardiac sarcoidosis recurrence post-heart transplant: A critical literature and case report.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2025Article
- Outcomes of catheter ablation in cardiac sarcoidosis patients with ventricular tachycardia: a propensity score-matched retrospective analysis.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025Article
- The Role of [18F]FDG PET-Based Radiomics and Machine Learning for the Evaluation of Cardiac Sarcoidosis: A Narrative Literature Review.Medicina (Kaunas, Lithuania) · 2025Review
58 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 8 institutions in 3 countries.
Funding
Abstract
Sarcoidosis is a complex disease with heterogeneous clinical presentations that can affect virtually any organ. Although the lung is typically the most common organ involved, combined pulmonary and cardiac sarcoidosis (CS) account for most of the morbidity and mortality associated with this disease. Pulmonary sarcoidosis can be asymptomatic or result in impairment in quality of life and end-stage, severe, and/or life-threatening disease. The latter outcome is seen almost exclusively in those with fibrotic pulmonary sarcoidosis, which accounts for 10% to 20% of pulmonary sarcoidosis patients. CS is problematic to diagnose and may cause significant morbidity and death from heart failure or ventricular arrhythmias. The diagnosis of CS usually requires surrogate cardiac imaging biomarkers, as endomyocardial biopsy has relatively low yield, even with directed electrophysiological mapping. Treatment of CS is often multifactorial, involving a combination of antigranulomatous therapy and pharmacotherapy for cardiac arrhythmias and/or heart failure in addition to device placement and cardiac transplantation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.