ArticleParasites & vectors2020
Demonstrating the presence of Ehrlichia canis DNA from different tissues of dogs with suspected subclinical ehrlichiosis.
Article in Parasites & vectors, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Molecular detection of Ehrlichia canis and Rickettsia rickettsii in tick-infested dogs from the city of Chihuahua, Mexico: phylogenetic analysis of the gp36 and ompA genes.Veterinary research communications · 2026Article
- Morphological remodeling of canine lymphocytes in Ehrlichia canis infection: quantitative analysis by scanning electron microscopy and fractal dimension.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2026Article
- Central Nervous System Vasculitis Due to Ehrlichia canis in a Dog.Veterinary medicine and science · 2025Article
- A multidimensional analysis of the risk of infection with Ehrlichia canis among urban dogs in Iquitos, Peru.Scientific reports · 2025Article
- Molecular survey of tick-borne pathogens in domestic dogs from a rural region within the buffer zone of a conservation unit in the Brazilian Caatinga biome.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2025Article
- TRP36-ELISA forHeliyon · 2024Article
- Molecular, epidemiological, and hematological evaluation inOpen veterinary journal · 2024Article
- Meta-analysis of tick-borne and other pathogens: Co-infection or co-detection? That is the question.Current research in parasitology & vector-borne diseases · 2024Review
- Molecular Detection and Characterization ofLife (Basel, Switzerland) · 2023Article
- First study on molecular detection of three major canine tick-borne pathogens in subclinically infected dogs in Chiang Mai, Thailand.Veterinary world · 2022Article
- Looking for Dog Blood Donors in an Endemic Area for Vector-Borne Infections of Central Italy.Animals : an open access journal from MDPI · 2022Article
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
backgroundNowadays, Ehrlichia canis receives increasing attention because of its great morbidity and mortality in animals. Dogs in the subclinical and chronic phases can be asymptomatic, and serological tests show cross-reactivity and fail to differentiate between current and past infections. Moreover, there could be low parasitaemia, and E. canis might be found only in target organs, hence causing results to be negative by polymerase chain reaction (PCR) on blood samples.
methodsWe evaluated by PCR the prevalence of E. canis in blood, liver, spleen, lymph node and bone marrow samples of 59 recently euthanised dogs that had ticks but were clinically healthy.
resultsIn total, 52.55% of the blood PCRs for E. canis were negative, yet 61.30% yielded positive results from tissue biopsies and were as follows: 63.15% from bone marrow; 52.63% from liver; 47.36% from spleen; and 15.78% from lymph node. In addition, 33% had infection in three tissues (spleen, liver and bone marrow).
conclusionsOur results show the prevalence of E. canis from tissues of dogs that were negative by blood PCR. Ehrlichia canis DNA in tissue was 30% lower in dogs that tested negative in PCR of blood samples compared to those that were positive. However, it must be taken into account that some dogs with negative results were positive for E. canis in other tissues.
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