ReviewJournal of medical case reports2020
Multiple myeloma presenting as an intramedullary spinal cord tumor: a case report and review of the literature.
Review in Journal of medical case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- Intradural extramedullary solitary plasmacytoma originating in the cervical spine in the setting of refractory multiple myeloma: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Spinal intradural lesion as manifestation of multiple myeloma: Illustrative case and systematic review of literature.Surgical neurology international · 2025Article
- A rare multiple myeloma complication as a spinal cord metastasis: A case report.Clinical case reports · 2023Article
- Multiple myeloma presenting as a cervical intraforaminal tumor: A case report and review of literature.Frontiers in surgery · 2023Article
- Infiltration of the spinal cord and peripheral nerves in multiple myeloma.Frontiers in oncology · 2022Article
- Intradural plasmacytoma originating from the filum terminale in the setting of multiple myeloma: illustrative case.Journal of neurosurgery. Case lessons · 2021Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExtramedullary disease in multiple myeloma often portends a worse diagnosis. In approximately 1% of cases, multiple myeloma may metastasize to the central nervous system as either leptomeningeal involvement or an intracranial, intraparenchymal lesion. Spinal cord metastases, however, are exceedingly rare. We present a case of spinal cord multiple myeloma as well as a literature review of reported cases. CASE PRESENTATION: A 66-year-old African American man with multiple myeloma presented with acute midthoracic pain and lower extremity paresis and paresthesia. Magnetic resonance imaging of the spine revealed two contrast-enhancing intramedullary enhancing lesions in the T1-T2 and T6-T7 cord. Resection with biopsy yielded a diagnosis of metastatic multiple myeloma.
conclusionTo date, only six cases of extramedullary disease to the spinal cord in patients with multiple myeloma have been reported, including our patient's case. In all cases, neurologic deficit was observed at presentation, and magnetic resonance imaging of the spine revealed an intramedullary, homogeneously enhancing lesion. Current evidence suggests worse prognosis in patients with extramedullary disease to the central nervous system, and treatment paradigms remain debatable.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.