Evidence map›Paper›PMID 33058964›Full record

ArticleAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2021

Inpatient Pediatric CKD Health Care Utilization and Mortality in the United States.

Zubin J Modi, Anne Waldo, David T Selewski, Jonathan P Troost, Debbie S Gipson

Open access · greenAbstract read
In one paragraph

Article in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Little kidneys amid large global inequities.Pediatric nephrology (Berlin, Germany) · 2026
    Review
  2. Pediatric kidney transplant disparities.World journal of clinical pediatrics · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. The impact of rural status on pediatric chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2024
    Article
  11. Patient-Reported Outcomes Over 24 Months in Pediatric CKD: Findings From the MyKidneyHealth Cohort Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2023
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zubin J ModiDivision of Pediatric Nephrology, Department of Pediatrics, University of Michigan, Ann Arbor, MI; Susan B. Meister Child Health Research and Evaluation Center, Department of Pediatrics, University of Michigan, Ann Arbor, MI. Electronic address: modiz@med.umich.edu.
Anne WaldoDepartment of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI.
David T SelewskiDivision of Pediatric Nephrology, Department of Pediatrics, Medical University of South Carolina, Charleston, SC.
Jonathan P TroostMichigan Institute for Clinical and Health Research, University of Michigan, Ann Arbor, MI.
Debbie S GipsonDivision of Pediatric Nephrology, Department of Pediatrics, University of Michigan, Ann Arbor, MI.
University of Michigan · USMedical University of South Carolina · US

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
RESEARCH TRAINING IN NEPHROLOGYT32DK007378 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PENNATHUR, SUBRAMANIAM · 1986 to 2019
$5.9M
NCATS NIH HHS UL1 TR002240NIDDK NIH HHS T32 DK007378
6 · The paper itself

Abstract

RATIONALE &

objectiveThe impact of chronic kidney disease (CKD) on inpatient health care use is unknown. This study aimed to describe the prevalence of pediatric CKD among children hospitalized in the United States and examine the association of CKD with hospital outcomes. STUDY

designCross-sectional national survey of pediatric discharges. SETTING &

participantsHospital discharges of children (aged>28 days to 19 years) with a chronic medical diagnosis included in the Healthcare Cost and Utilization Project Kids' Inpatient Database for 2006, 2009, 2012, and 2016. PREDICTOR: Presence of primary or coexisting CKD as identified by diagnosis codes. OUTCOMES: Length of stay (LOS), cost, and mortality. ANALYTICAL APPROACH: Multivariable analysis using Poisson, gamma, and logistic regressions were performed for LOS, cost, and mortality, respectively.

resultsA chronic medical condition was present in 6,524,745 estimated discharges during the study period and CKD was present among 3.9% of discharges (96.1% without CKD). Those with CKD had a longer LOS (median of 2.8 [IQR, 1.4-6.0] days compared with 1.8 [IQR, 1.0-4.4] days for those without a CKD diagnosis; P<0.001). Median cost was higher in the CKD group compared with the group without CKD, at $8,755 (IQR, $4,563-18,345) and $5,016 (IQR, $2,860-10,109) per hospitalization, respectively (P<0.001). Presence of CKD was associated with a longer LOS (29.9% [95% CI, 27.2%-32.6%] longer than those without CKD), higher cost (61.3% [95% CI, 57.4%-65.4%] greater than those without CKD), and higher risk for mortality (OR, 1.51 [95% CI, 1.40-1.63]). LIMITATIONS: Lack of access to and adjustment for confounders including patient readmission and laboratory data.

conclusionsPediatric CKD was associated with longer LOS, higher costs, and higher risk for mortality compared with hospitalizations with other chronic illnesses. Further studies are needed to better understand the health care needs and delivery of care to hospitalized children with CKD.

Indexed as

Patient Acceptance of Health CareChildCohort StudiesCross-Sectional StudiesDatabases, FactualFemaleHospitalizationHumansMaleRenal Insufficiency, ChronicUnited Statesadolescentschildrenchronic illnessChronic kidney disease (CKD)health care costshospitalizationhospital utilizationin-hospital mortalityinpatient dischargelength of stay (LOS)medical complexitypediatric

Identifiers

PMID33058964
PMCPMC8485635
OpenAlexW3092070037

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.