ArticleJournal of cachexia, sarcopenia and muscle2020
Associations of combined genetic and epigenetic scores with muscle size and muscle strength: a pilot study in older women.
Article in Journal of cachexia, sarcopenia and muscle, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Biomarkers associated with lower limb muscle function in individuals with sarcopenia: a systematic review.Journal of cachexia, sarcopenia and muscle · 2022Pooled it
- Identifying risk factors for sarcopenia using machine learning: insights from multimodal data.European geriatric medicine · 2025Article
- Dietary polyphenols and sarcopenia: epigenetic mechanisms and geroscience perspectives for muscle health in aging.Frontiers in aging · 2025Review
- Epigenetics of Skeletal Muscle Atrophy.International journal of molecular sciences · 2024Review
- Development of Continuous Assessment of Muscle Quality and Frailty in Older Patients Using Multiparametric Combinations of Ultrasound and Blood Biomarkers: Protocol for the ECOFRAIL Study.JMIR research protocols · 2024Article
- Epigenome-wide association study identifies DNA methylation loci associated with handgrip strength in Chinese monozygotic twins.Frontiers in cell and developmental biology · 2024Article
- Hallmarks of ageing in human skeletal muscle and implications for understanding the pathophysiology of sarcopenia in women and men.Clinical science (London, England : 1979) · 2023Article
- Identification and Characterization of Genomic Predictors of Sarcopenia and Sarcopenic Obesity Using UK Biobank Data.Nutrients · 2023Article
- Polygenic Models Partially Predict Muscle Size and Strength but Not Low Muscle Mass in Older Women.Genes · 2022Article
- Pathogenesis of sarcopenia and the relationship with fat mass: descriptive review.Journal of cachexia, sarcopenia and muscle · 2022Review
- Musculoskeletal Health in Active Ambulatory Men with Cerebral Palsy and the Impact of Vitamin D.Nutrients · 2021Article
- Static one-leg standing balance test as a screening tool for low muscle mass in healthy elderly women.Aging clinical and experimental research · 2021Article
- A Genome-Wide Association Study Identifies Novel Risk Loci for Sarcopenia in a Taiwanese Population.Journal of inflammation research · 2021Article
- The Association of Multiple Gene Variants with Ageing Skeletal Muscle Phenotypes in Elderly Women.Genes · 2020Article
- Associations of combined genetic and epigenetic scores with muscle size and muscle strength: a pilot study in older women.Journal of cachexia, sarcopenia and muscle · 2020Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInter-individual variance in skeletal muscle is closely related to genetic architecture and epigenetic regulation. Studies have examined genetic and epigenetic relationships with characteristics of ageing muscle separately, while no study has combined both genetic and epigenetic profiles in ageing muscle research. The aim of this study was to evaluate the association between combined genetic and methylation scores and skeletal muscle phenotypes in older women.
methodsForty-eight older Caucasian women (aged 65-79 years) were included in this study. Biceps brachii thickness and vastus lateralis anatomical cross-sectional area (ACSA
resultsMS
conclusionsOur results improve the understanding of inter-individual variance in muscular characteristics of older women and suggest a possible application of a sarcopenia-driven methylation score to muscle strength estimation in older women while the combination with a genetic score still needs to be further studied.
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Registered trials
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