Evidence map›Paper›PMID 33058321›Full record

ReviewEuropean journal of neurology2021

EAN consensus statement for management of patients with neurological diseases during the COVID-19 pandemic.

T J von Oertzen, A Macerollo, M A Leone, E Beghi, M Crean, S Oztuk, C Bassetti, A Twardzik, D Bereczki, G Di Liberto and 18 more

Registry-linked trialOpen access · hybridAbstract readReviewConsensus Statement
In one paragraph

Review in European journal of neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04611295 (TELENeurological Evaluation and Support for the Emergency Department), which is not on this map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04611295 naunknown statusnot on this map

TELENeurological Evaluation and Support for the Emergency Department (TELENS-ED): an Open-label Clinical Trial

TypeinterventionalSponsorAzienda Ospedaliero-Universitaria di ModenaRan2020 to 2022Enrolled88ConditionsEmergencies, Neurologic DisorderArmsTeleneurological evaluation and support
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. European Academy of Neurology: First 10 years.European journal of neurology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 20 institutions in 13 countries.

T J von OertzenFaculty of Medicine, Johannes-Kepler Universität, Linz, Austria.ORCID 0000-0003-2164-7842
A MacerolloWalton Centre NHS Foundation Trust, Liverpool, UK.ORCID 0000-0003-4322-2706
M A LeoneUO Neurologia, Fondazione IRCCS 'Casa Sollievo della Sofferenza', San Giovanni Rotondo, Italy.ORCID 0000-0002-6339-5738
E BeghiDepartment of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.ORCID 0000-0003-2542-0469
M CreanEuropean Academy of Neurology, Head Office, Vienna, Austria.
S OztukDepartment of Neurology, Faculty of Medicine, Selcuk University, Konya, Turkey.
C BassettiDepartment of Neurology, Inselspital, University of Bern, Bern, Switzerland.ORCID 0000-0002-4535-0245
A TwardzikEuropean Academy of Neurology, Head Office, Vienna, Austria.
D BereczkiDepartment of Neurology, Semmelweis University, Budapest, Hungary.ORCID 0000-0002-8374-0500
G Di LibertoDepartment of Pathology and Immunology, Geneva Faculty of Medicine, Geneva, Switzerland.
R HelbokDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
C Oreja-GuevaraDepartment of Neurology, Hospital Clínico San Carlos, Madrid, Spain.
A PisaniNeurology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.ORCID 0000-0002-8432-594X
A SauerbierDepartment of Neurology, University Hospital Cologne, Cologne, Germany.
J SellnerDepartment of Neurology, Landesklinikum Mistelbach-Gänserndorf, Mistelbach, Austria.ORCID 0000-0001-8749-5533
R SoffiettiDivision of Neuro-Oncology, Department of Neuroscience, University of Turin, Turin, Italy.
M ZeddeNeurology Unit, Neuromotor and Rehabilitation Department, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
E BianchiDepartment of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
B BodiniDepartment of Neurology, Saint-Antoine Hospital, APHP, Sorbonne University, Paris, France.
F CavallieriNeurology Unit, Neuromotor and Rehabilitation Department, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.ORCID 0000-0001-5836-1982
L CampiglioDivision of Neurology, 'Aldo Ravelli' Research Center, Department of Neurology, University of Milan and ASST Santi Paolo e Carlo, Milan, Italy.
L F MaiaDepartment of Neurology, Centro Hospitalar Universitário do Porto, Porto, Portugal.
A PrioriDivision of Neurology, 'Aldo Ravelli' Research Center, Department of Neurology, University of Milan and ASST Santi Paolo e Carlo, Milan, Italy.
M RakusaDepartment of Neurology, University Medical Centre Maribor, Maribor, Slovenia.ORCID 0000-0003-4433-3985
P TabaDepartment of Neurology and Neurosurgery, Institute of Clinical Medicine, University of Tartu, Tartu, Estonia.ORCID 0000-0002-5439-1022
E MoroDivision of Neurology, CHU of Grenoble, Grenoble Alpes University, Grenoble Institute of Neurosciences, Grenoble, France.ORCID 0000-0002-7968-5908
T M JenkinsSheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, UK.
EANcore COVID-19 task force
AOL (United States) · USEuropean Academy of Neurology · ATMario Negri Institute for Pharmacological Research · ITAzienda Sanitaria Unità Locale di Reggio Emilia · ITCasa Sollievo della Sofferenza · ITCentre Hospitalier Universitaire de Grenoble · FRCentro Hospitalar do Porto · PTInnsbruck Medical University · ATJohannes Kepler University of Linz · ATNeuroscience Institute · ITParacelsus Medical University · ATSelçuk University · TRSemmelweis University · HUSheffield Teaching Hospitals NHS Foundation Trust · GBSorbonne Université · FRUniversidad Complutense de Madrid · ESUniversity Clinical Centre Maribor · SIUniversity Hospital Cologne · DEUniversity of Bern · CHUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThe recent SARS-CoV-2 pandemic has posed multiple challenges to the practice of clinical neurology including recognition of emerging neurological complications and management of coexistent neurological diseases. In a fast-evolving pandemic, evidence-based studies are lacking in many areas. This paper presents European Academy of Neurology (EAN) expert consensus statements to guide neurologists caring for patients with COVID-19.

methodsA refined Delphi methodology was applied. In round 1, statements were provided by EAN scientific panels (SPs). In round 2, these statements were circulated to SP members not involved in writing them, asking for agreement/disagreement. Items with agreement >70% were retained for round 3, in which SP co-chairs rated importance on a five-point Likert scale. Results were graded by importance and reported as consensus statements.

resultsIn round one, 70 statements were provided by 23 SPs. In round two, 259/1061 SP member responses were received. Fifty-nine statements obtained >70% agreement and were retained. In round three, responses were received from 55 co-chairs of 29 SPs. Whilst general recommendations related to prevention of COVID-19 transmission had high levels of agreement and importance, opinion was more varied concerning statements related to therapy.

conclusionThis is the first structured consensus statement on good clinical practice in patients with neurological disease during the COVID-19 pandemic that provides immediate guidance for neurologists. In this fast-evolving pandemic, a rapid response using refined Delphi methodology is possible, but guidance may be subject to change as further evidence emerges.

Indexed as

COVID-19PandemicsPatient Care ManagementDelphi TechniqueGuidelines as TopicHumansNervous System DiseasesNeurologychronic diseaseCOVID-19humanneurologypractice guideline

Identifiers

PMID33058321
PMCPMC7675361
OpenAlexW3093330896

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.