ReviewPain and therapy2020
Pain and Frailty in Hospitalized Older Adults.
Review in Pain and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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Who cites it
27 citing papers in PubMed, 45 citations in OpenAlex.
- Pain and depression mediate the relationship between multimorbidity and frailty in older adults with diabetes.Scientific reports · 2026Article
- Frailty in rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis: Current evidence and knowledge gaps.Therapeutic advances in musculoskeletal disease · 2026Review
- From age to frailty: redefining chronic pain characterization.Aging clinical and experimental research · 2025Article
- Development and validation of a novel frailty model for the patients with newly diagnosed multiple myeloma.European journal of medical research · 2025Article
- Pain in Osteoporosis: Current and Future Strategies.Drugs & aging · 2025Review
- The relation between radiographic knee osteoarthritis severity and pain is stronger among more frail people.Clinical rheumatology · 2025Article
- Longitudinal association between frailty and pain in three prospective cohorts of older population.The journal of nutrition, health & aging · 2025Article
- Splenic and portal venous flow associated with frailty and sarcopenia in older outpatients with cardiovascular disease.BMC geriatrics · 2025Article
- The effects of frailty on opioid consumption after total knee arthroplasty.Journal of anesthesia · 2025Article
- Association Between Pain and Frailty in Middle-Aged and Older Patients: The Mediating Roles of Sleep and Mood.Clinical interventions in aging · 2025Article
- Association between frailty and pain in older people at high risk of future hospitalization.Frontiers in pain research (Lausanne, Switzerland) · 2025Article
- Frailty as a mediator of postoperative delirium in older adults undergoing orthopedic surgery: A causal mediation analysis.International journal of nursing studies advances · 2024Article
- Pain management inequities by demographic and geriatric-related variables in older adult inpatients.Journal of the American Geriatrics Society · 2024Article
- Preoperative frailty predicts postoperative pain after total knee arthroplasty in older patients: a prospective observational study.European geriatric medicine · 2024Observational
- Impact of frailty severity and severe pain on cognitive function for community-dwelling older adults with arthritis: a cross-sectional study in Korea.Scientific reports · 2024Article
- Agreement Between a Colorimetric Assay and Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry for Quantifying Paracetamol Plasma Concentrations.The AAPS journal · 2024Article
- The vicious cycle of frailty and pain: a two-sided causal relationship revealed.Frontiers in medicine · 2024Article
- Cardiometabolic Disorders Are Important Correlates of Vulnerability in Hospitalized Older Adults.Nutrients · 2023Article
- Haemophilia and Fragility Fractures: From Pathogenesis to Multidisciplinary Approach.International journal of molecular sciences · 2023Review
- Frailty and pain in an acute private hospital: an observational point prevalence study.Scientific reports · 2023Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPain and frailty are prevalent conditions in the older population. Many chronic diseases are likely involved in their origin, and both have a negative impact on quality of life. However, few studies have analysed their association.
methodsIn light of this knowledge gap, 3577 acutely hospitalized patients 65 years or older enrolled in the REPOSI register, an Italian network of internal medicine and geriatric hospital wards, were assessed to calculate the frailty index (FI). The impact of pain and some of its characteristics on the degree of frailty was evaluated using an ordinal logistic regression model after adjusting for age and gender.
resultsThe prevalence of pain was 24.7%, and among patients with pain, 42.9% was regarded as chronic pain. Chronic pain was associated with severe frailty (OR = 1.69, 95% CI 1.38-2.07). Somatic pain (OR = 1.59, 95% CI 1.23-2.07) and widespread pain (OR = 1.60, 95% CI 0.93-2.78) were associated with frailty. Osteoarthritis was the most common cause of chronic pain, diagnosed in 157 patients (33.5%). Polymyalgia, rheumatoid arthritis and other musculoskeletal diseases causing chronic pain were associated with a lower degree of frailty than osteoarthritis (OR = 0.49, 95%CI 0.28-0.85).
conclusionsChronic and somatic pain negatively affect the degree of frailty. The duration and type of pain, as well as the underlying diseases associated with chronic pain, should be evaluated to improve the hospital management of frail older people.
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